TGT may stand for:
Chemistry
- Tagetitoxin
- TRNA-guanine15 transglycosylase, an enzyme
- Cysteine, an amino acid coded TGT
Arts and media
- TGT (group), R&B supergroup formed by Tyrese, Ginuwine, and Tank
- Thailand's Got Talent, Thai reality television series
- The Grand Tour, British motoring programme
Businesses
- TGT Oil and Gas Services
- Target Corporation, NYSE stock ticker
- Tennessee Gas Transmission Company
Other uses
- Tamangic languages (Tamang, Gurung, Thakali and others)
- Tanga Airport, by IATA code, in Tanga, Tanzania
- Target (disambiguation)
- Ticket Granting Ticket, in network security
- Transitional Government of Tigray, in Ethiopia
- Trained Graduate Teacher, a teacher who holds a degree for teaching students
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