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TJAP1
Identifiers
Aliases	TJAP1, PILT, TJP4, tight junction associated protein 1
External IDs	OMIM: 612658; MGI: 1921344; HomoloGene: 12534; GeneCards: TJAP1; OMA:TJAP1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.1 Start 43,477,523 bp End 43,506,556 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17|17 C Start 46,568,777 bp End 46,593,952 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte sural nerve C1 segment inferior ganglion of vagus nerve optic nerve inferior olivary nucleus left ovary gastrocnemius muscle right ovary body of uterus Top expressed in muscle of thigh ventricular zone neural layer of retina lip vestibular sensory epithelium zygote gastrula yolk sac primary visual cortex epiblast More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm cell junction endosome trans-Golgi network plasma membrane bicellular tight junction Golgi apparatus Biological process Golgi organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 93643 74094 Ensembl ENSG00000137221 ENSMUSG00000012296 UniProt Q5JTD0 Q9DCD5 RefSeq (mRNA) NM_001146016 NM_001146017 NM_001146018 NM_001146019 NM_001146020 NM_080604 NM_001350561 NM_001350562 NM_001350563 NM_001350564 NM_001350565 NM_001350566 NM_001350567 NM_001350568 NM_001350569 NM_001350570 NM_001394538 NM_001394539 NM_001394540 NM_001394541 NM_001394542 NM_001394543 NM_001394544 NM_001394545 NM_001252473 NM_001252474 NM_001252475 NM_028751 RefSeq (protein) NP_001139488 NP_001139489 NP_001139490 NP_001139491 NP_001139492 NP_542171 NP_001337490 NP_001337491 NP_001337492 NP_001337493 NP_001337494 NP_001337495 NP_001337496 NP_001337497 NP_001337498 NP_001337499 NP_001239402 NP_001239403 NP_001239404 NP_083027 Location (UCSC) Chr 6: 43.48 – 43.51 Mb Chr 17: 46.57 – 46.59 Mb PubMed search
Wikidata
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Tight junction-associated protein 1 is a protein that in humans is encoded by the TJAP1 gene.

Interactions

TJAP1 has been shown to interact with DLG1.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000137221 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000012296 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Kawabe H, Nakanishi H, Asada M, Fukuhara A, Morimoto K, Takeuchi M, Takai Y (Dec 2001). "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells". J Biol Chem. 276 (51): 48350–5. doi:10.1074/jbc.M107335200. PMID 11602598.
6. "Entrez Gene: TJAP1 tight junction associated protein 1 (peripheral)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Xavier R, Rabizadeh S, Ishiguro K, et al. (2004). "Discs large (Dlg1) complexes in lymphocyte activation". J. Cell Biol. 166 (2): 173–8. doi:10.1083/jcb.200309044. PMC 2172307. PMID 15263016.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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