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TOM1L2
Identifiers
Aliases	TOM1L2, target of myb1 like 2 membrane trafficking protein
External IDs	OMIM: 615519; MGI: 2443306; HomoloGene: 44901; GeneCards: TOM1L2; OMA:TOM1L2 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17p11.2 Start 17,843,511 bp End 17,972,422 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B2 Start 60,117,540 bp End 60,243,731 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve apex of heart right auricle left ventricle right frontal lobe right lobe of thyroid gland lateral nuclear group of thalamus skin of leg Amygdala right hemisphere of cerebellum Top expressed in habenula pontine nuclei superior colliculus dorsal tegmental nucleus central gray substance of midbrain dentate gyrus of hippocampal formation granule cell subiculum ventral tegmental area primary visual cortex superior frontal gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function clathrin binding protein binding protein kinase binding Cellular component extracellular exosome intracellular anatomical structure Biological process protein transport intracellular protein transport negative regulation of mitotic nuclear division signal transduction transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 146691 216810 Ensembl ENSG00000175662 ENSMUSG00000000538 UniProt Q6ZVM7 Q5SRX1 RefSeq (mRNA) NM_001033551 NM_001082968 NM_001288786 NM_001288787 NM_001288788 NM_001288789 NM_144678 NM_001350331 NM_001350332 NM_001350333 NM_001039092 NM_001039093 NM_153080 NM_001359810 RefSeq (protein) NP_001028723 NP_001076437 NP_001275715 NP_001275716 NP_001275717 NP_001275718 NP_001337260 NP_001337261 NP_001337262 NP_001034181 NP_001034182 NP_694720 NP_001346739 NP_001390817 NP_001390820 NP_001390822 NP_001390824 NP_001390825 Location (UCSC) Chr 17: 17.84 – 17.97 Mb Chr 11: 60.12 – 60.24 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

TOM1-like protein 2 is a protein that in humans is encoded by the TOM1L2 gene.

See also

• TOM1, target of Myb1 membrane trafficking protein
• TOM1L1

References

1. ^ GRCh38: Ensembl release 89: ENSG00000175662 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000000538 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Seranski P, Heiss NS, Dhorne-Pollet S, Radelof U, Korn B, Hennig S, Backes E, Schmidt S, Wiemann S, Schwarz CE, Lehrach H, Poustka A (May 1999). "Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes". Genomics. 56 (1): 1–11. doi:10.1006/geno.1998.5647. PMID 10036180.
6. "Entrez Gene: TOM1L2 target of myb1-like 2 (chicken)".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Bi W, Yan J, Stankiewicz P, et al. (2002). "Genes in a Refined Smith-Magenis Syndrome Critical Deletion Interval on Chromosome 17p11.2 and the Syntenic Region of the Mouse". Genome Res. 12 (5): 713–28. doi:10.1101/gr.73702. PMC 186594. PMID 11997338.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Mol. Cell. Proteomics. 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Katoh Y, Imakagura H, Futatsumori M, Nakayama K (2006). "Recruitment of clathrin onto endosomes by the Tom1-Tollip complex". Biochem. Biophys. Res. Commun. 341 (1): 143–9. doi:10.1016/j.bbrc.2005.12.156. PMID 16412388.
• Franco M, Furstoss O, Simon V, et al. (2006). "The Adaptor Protein Tom1L1 Is a Negative Regulator of Src Mitogenic Signaling Induced by Growth Factors". Mol. Cell. Biol. 26 (5): 1932–47. doi:10.1128/MCB.26.5.1932-1947.2006. PMC 1430241. PMID 16479011.

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