This is a table of volume of distribution (Vd) for various medication. For comparison, those with a Vd L/kg body weight of less than 0.2 are mainly distributed in blood plasma, 0.2-0.7 mostly in the extracellular fluid and those with more than 0.7 are distributed throughout total body water.
Medication | Vd L/kg body weight |
---|---|
heparin | 0.05-0.1 |
insulin | 0.05-0.1 |
warfarin | 0.1-0.2 |
sulfamethoxazole | 0.1-0.2 |
glibenclamide | 0.1-0.2 |
atenolol | 0.1-0.2 |
NXY-059 | 0.1-0.2 |
tubocurarine | 0.2-0.4 |
theophylline | 0.4-0.7 |
ethanol | 0.7-0.9 |
neostigmine | 0.7-0.9 |
phenytoin | 0.7-0.9 |
methotrexate | 1-2 |
indometacin | 1-2 |
paracetamol | 1-2 |
diazepam | 1-2 |
lidocaine | 1-2 |
glyceryl trinitrate | 2-5 |
morphine | 2-5 |
propranolol | 2-5 |
digoxin | 2-5 |
chlorpromazine | 2-5 |
nortriptyline | 2-5 |
chloroquine | 200 |
References & footnotes
- ^ Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 103
- ^ Estimated with a body weight of 70 kg.