The Sign can refer to:
- The Sign (Ace of Base album), an alternate name for the Ace of Base album Happy Nation
- "The Sign" (song), a 1993 hit from this album
- The Sign (Crystal Lake album), the third studio album by Japanese metalcore band Crystal Lake
- "The Sign" (Bluey), an episode of the Australian animated TV series Bluey
- "The Sign" (Agents of S.H.I.E.L.D.), an episode of the American TV series Agents of S.H.I.E.L.D.
- "The Sign", a song by Lizzo from her fourth studio album Special
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