Thuillier is a surname. Notable people with the surname include:
- Elisabeth Thuillier (fl. 1890s-1920s), French colourist
- Émilie Thuillier, Canadian politician
- Emilio Thuillier (1868–1940), Spanish actor
- Harry Thuillier (1925–2011), Irish fencer
- Henry Edward Landor Thuillier (1813–1906), British surveyor in India
- Henry Fleetwood Thuillier (1868–1953), British Army officer
- Henry Shakespear Thuillier (1895–1982), British Army officer
- Henry Ravenshaw Thuillier (1838–1922), British surveyor in India
- Jacques Thuillier (1928– 2011), French art historian
- Jean Thuillier (born 1921), French novelist
- Leslie de Malapert Thuillier (1905–1999), British Army officer
- Louis Thuillier (1856–1883), French biologist
- Luc Thuillier (born 1964), French actor
- Nick Thuillier, Irish fencer
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