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Tigloidine

Clinical data
Trade names	Tropigline
Identifiers
IUPAC name (8-Methyl-8-azabicyclooctan-3-yl) (E)-2-methylbut-2-enoate
CAS Number	495-83-0
PubChem CID	5281865
ChemSpider	16736065
UNII	75GK1SV4EI
KEGG	C10868
ChEBI	CHEBI:9593
ChEMBL	ChEMBL2107120
ECHA InfoCard	100.007.101
Chemical and physical data
Formula	C13H21NO2
Molar mass	223.316 g·mol
3D model (JSmol)	Interactive image
SMILES CC=C(C)C(=O)OC1CC2CCC(C1)N2C
InChI InChI=1S/C13H21NO2/c1-4-9(2)13(15)16-12-7-10-5-6-11(8-12)14(10)3/h4,10-12H,5-8H2,1-3H3/b9-4+ Key:UVHGSMZRSVGWDJ-RUDMXATFSA-N

Tigloidine is a tropane alkaloid that naturally occurs as a minor constituent of a number of solanaceous plants, including Duboisia myoporoides, Physalis peruviana, and Mandragora turcomanica.

It was formerly marketed as an antiparkinsonian drug under the trade name Tropigline.

References

1. Barger G, Martin WF, Mitchell W (1937). "383. The minor alkaloids of Duboisia myoporoides". Journal of the Chemical Society (Resumed): 1820. doi:10.1039/JR9370001820. hdl:1842/35366.
2. Beresford PJ, Woolley JG (1974). "Biosynthesis of ticloidine in Physalis peruviana". Phytochemistry. 13 (10): 2143–2144. Bibcode:1974PChem..13.2143B. doi:10.1016/0031-9422(74)85016-8.
3. "Approved Names". British Medical Journal. 1 (5080): 1175. 1958. doi:10.1136/bmj.1.5080.1175. PMC 2028565.
4. Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 1663–. ISBN 978-3-88763-075-1.

• Tropane alkaloids
• Antiparkinsonian agents