| Toby Gibson | |
|---|---|
| Born | Toby James Gibson |
| Alma mater | University of Edinburgh (BSc) University of Cambridge (PhD) |
| Known for | Clustal |
| Scientific career | |
| Fields | Computational biology Bioinformatics Short linear motifs Protein interactions Sequence alignment |
| Institutions | Laboratory of Molecular Biology European Molecular Biology Laboratory |
| Thesis | Studies on the Epstein-Barr virus genome (1984) |
| Website | www |
Toby James Gibson is a group leader and biochemist at the European Molecular Biology Laboratory (EMBL) in Heidelberg known for his work on Clustal. According to Nature, Gibson's co-authored papers describing Clustal are among the top ten most highly cited scientific papers of all time.
Education
Gibson was educated at the University of Edinburgh and went on to his PhD at the University of Cambridge in 1984 on the genome of the Epstein–Barr virus while working in the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB).
Career and research
Gibson was a postdoctoral research fellow with Sydney Brenner before moving to EMBL in 1986. He was appointed a staff scientist in 1991 and a team leader in 1996 where he has worked since.
Gibson’s research interests are in computational biology, bioinformatics, short linear motifs, protein–protein interactions and biological sequence alignment. His laboratory developed and hosts the Eukaryotic Linear Motif (ELM) resource.
References
- ^ Toby Gibson publications indexed by Google Scholar
- ^ Thompson, Julie D.; Higgins, Desmond G.; Gibson, Toby J. (1994). "CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice". Nucleic Acids Research. 22 (22): 4673–4680. doi:10.1093/nar/22.22.4673. ISSN 0305-1048. PMC 308517. PMID 7984417.
- Toby Gibson publications from Europe PubMed Central
- ^ Thompson, J. (1997). "The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools". Nucleic Acids Research. 25 (24): 4876–4882. doi:10.1093/nar/25.24.4876. ISSN 1362-4962. PMC 147148. PMID 9396791.
- Thompson, J. D.; Higgins, D. G.; Gibson, T. J. (1994). "CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice". Nucleic Acids Research. 22 (22): 4673–4680. doi:10.1093/nar/22.22.4673. PMC 308517. PMID 7984417.
- Van Noorden, R.; Maher, B.; Nuzzo, R. (2014). "The top 100 papers: Nature explores the most-cited research of all time". Nature. 514 (7524): 550–3. doi:10.1038/514550a. PMID 25355343.
- ^ Anon (2019). "Toby (James) Gibson: EMBL, Heidelberg, Germany". uni-halle.de. Martin Luther University of Halle-Wittenberg. Archived from the original on 2019-07-05.
- Gibson, Toby James (1984). Studies on the Epstein-Barr virus genome. cam.ac.uk (PhD thesis). University of Cambridge. OCLC 499859334. EThOS uk.bl.ethos.352786.
- Kumar, Manjeet; Gouw, Marc; Michael, Sushama; Sámano-Sánchez, Hugo; Pancsa, Rita; Glavina, Juliana; Diakogianni, Athina; Valverde, Jesús Alvarado; Bukirova, Dayana; Čalyševa, Jelena; Palopoli, Nicolas; Davey, Norman E; Chemes, Lucía B; Gibson, Toby J (2019). "ELM—the eukaryotic linear motif resource in 2020". Nucleic Acids Research. doi:10.1093/nar/gkz1030. ISSN 0305-1048. PMC 7145657. PMID 31680160.