Topley may refer to:
Surname:
- Don Topley (born 1964), former English cricketer
- Lady Sophia Topley (born 1957), daughter of the 11th Duke of Devonshire
- Martina Topley-Bird, British vocalist
- Peter Topley (born 1950), former English cricketer
- Reece Topley (born 1994), English cricketer
- William James Topley (1845–1930), Canadian photographer based in Ottawa, Ontario
- William Topley (geologist) FRS (1841–1894), British geologist
- William Topley (musician), British musician
- William Whiteman Carlton Topley FRS (1886–1944), British bacteriologist
Places:
- Topley, British Columbia, small town in northern British Columbia, located on the Trans-Canada highway
- Topley Landing Provincial Park, provincial park in British Columbia, Canada
- Topley Landing, British Columbia, small town near the provincial park
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