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Travoprost/timolol

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Fixed-dose combination medication

Pharmaceutical compound
Travoprost/timolol
Combination of
TravoprostProstaglandin analog
TimololBeta-blocker
Clinical data
Trade namesDuotrav
AHFS/Drugs.comUK Drug Information
Pregnancy
category
  • AU: C
Routes of
administration
Eye drops
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • EU: Rx-only
Identifiers
CAS Number
KEGG

Travoprost/timolol, sold under the brand name Duotrav among others, is a fixed-dose combination medication used for the treatment of glaucoma. It contains travoprost and timolol maleate.

It was approved for medical use in the European Union in April 2006.

References

  1. ^ "Travoprost/timolol Product Information" (PDF). TGA eBS. Retrieved 23 May 2021.
  2. "DUOTRAV travoprost 0.004% and timolol 0.5% (as maleate) eye drop solution". Department of Health. Australian Government.
  3. "DuoTrav eye drops solution - Summary of Product Characteristics (SmPC)". (emc). 14 June 2018. Retrieved 30 October 2020.
  4. ^ "Duotrav EPAR". European Medicines Agency (EMA). 17 September 2018. Retrieved 30 October 2020.
  5. Cheng JW, Cheng SW, Gao LD, Lu GC, Wei RL (2012). "Intraocular pressure-lowering effects of commonly used fixed-combination drugs with timolol: a systematic review and meta-analysis". PLOS ONE. 7 (9): e45079. Bibcode:2012PLoSO...745079C. doi:10.1371/journal.pone.0045079. PMC 3441590. PMID 23028770.
  6. Konstas AG, Quaranta L, Realini T (April 2012). "Overview of the travoprost /timolol BAK-free fixed combination". Expert Opinion on Pharmacotherapy. 13 (5): 757–66. doi:10.1517/14656566.2012.662485. PMID 22360540. S2CID 24160793.
  7. Denis P (February 2011). "Travoprost/timolol fixed combination in the management of open-angle glaucoma: a clinical review". Expert Opinion on Pharmacotherapy. 12 (3): 463–71. doi:10.1517/14656566.2011.551007. PMID 21254951. S2CID 46258207.

External links

Drugs used for glaucoma preparations and miosis (S01E)
Sympathomimetics
Parasympathomimetics
muscarinic
muscarinic/nicotinic
acetylcholinesterase inhibitors
Carbonic anhydrase inhibitors/
(sulfonamides)
Beta blocking agents
Prostaglandin analogues (F)
Other agents
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