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Trudy Frances Charlene Mackay FRS (born 10 September 1952) is the director of Clemson University's Center for Human Genetics located on the campus of the Greenwood Genetic Center. She is recognized as one of the world's leading authorities on the genetics of complex traits. Mackay is also the Self Family Chair in Human Genetics and Professor of Genetics and Biochemistry at Clemson University.

Mackay is a member of the National Academy of Sciences (2010).

Mackay was formerly the William Neal Reynolds and Distinguished University Professor at North Carolina State University, where she specialized in quantitative genetics. She is responsible for establishing the Drosophila Genetic Reference Panel.

Education

Mackay received a Bachelor of Science degree in 1974 and Master of Science degree in 1976 in Biology from Dalhousie University. She completed postgraduate study at the University of Edinburgh with a PhD in genetics awarded in 1979 for research supervised by Alan Robertson.

Career and research

Mackay's research investigates the environmental and genetic factors that influence quantitative traits. These phenotypic traits include height or weight and are represented by continuous, rather than discrete, values. Her work is undertaken by studying the impact of natural variants and mutations on many behavioural, morphological, physiological and life history traits in fruit flies, which she uses as a model organism.

The broad importance of such traits gives Mackay's work potential application in many areas — from improving plant breeding and animal breeding to the treatment of human diseases. Mackay is the co-author with Douglas Scott Falconer of the fourth edition of the widely used and highly cited textbook, Introduction to Quantitative Genetics, published in 1996.

Awards and honours

Mackay was elected a Fellow of the Royal Society (FRS) in 2006. She was awarded the Genetics Society of America Medal in 2004 and the Wolf Prize in Agriculture in 2016. She was elected to the American Philosophical Society in 2021. She is a recipient of Trinity College’s Dawson Prize in Genetics in 2018. She was elected Fellow of the American Association for the Advancement of Science in 2003. She became a member of the American Academy of Arts and Sciences in 2005.

Personal life

Mackay married Robert R. H. Anholt in 1990.

References

1. ^ Mackay, Trudy Frances Charlene (1979). Genetic variation in varying environments (PhD thesis). University of Edinburgh. hdl:1842/11082. OCLC 757072704. EThOS uk.bl.ethos.502971.
2. ^ Anon (2017). "Mackay, Prof. Trudy Frances Charlene, (Mrs R. R. H. Anholt)". Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.151464. (Subscription or UK public library membership required.)
3. ^ Maguire, Marti (February 6, 2016). "Tar Heel: Trudy Mackay works with fruit flies to solve genetic mysteries". The News & Observer. Retrieved 16 February 2016.
4. "Renowned scientist named director of Clemson's Center for Human Genetics". Newsstand | Clemson University News and Stories, South Carolina. Archived from the original on 2020-09-07. Retrieved 2018-08-24.
5. "The Greenwood Genetic Center". www.ggc.org. Retrieved 2018-08-24.
6. "Salute to Faculty Excellence | College of Science, Clemson University, South Carolina". www.clemson.edu. Archived from the original on 2020-09-07. Retrieved 2018-08-24.
7. "Clemson University, South Carolina". www.clemson.edu. Retrieved 2018-08-24.
8. "Trudy Mackay". www.nasonline.org. Retrieved 2018-08-24.
9. "Mackay Homepage". Archived from the original on 2008-04-23. Retrieved 2008-07-21. Faculty webpage
10. Mackay, Trudy (2006). "Trudy Mackay". Current Biology. 16 (17): R659 – R661. doi:10.1016/j.cub.2006.08.016. ISSN 0960-9822. PMID 16991214.
11. "NC State: Trudy Mackay". youtube.com. YouTube. Archived from the original on 2021-12-21.
12. Mackay, Trudy F. C.; Stone, Eric A.; Ayroles, Julien F. (2009). "The genetics of quantitative traits: challenges and prospects". Nature Reviews Genetics. 10 (8): 565–577. doi:10.1038/nrg2612. ISSN 1471-0056. PMID 19584810. S2CID 1431889.
13. Mackay, Trudy F. C. (2001). "The Genetic Architecture of Quantitative Traits". Annual Review of Genetics. 35 (1): 303–339. doi:10.1146/annurev.genet.35.102401.090633. ISSN 0066-4197. PMID 11700286.
14. Manolio, Teri A.; Collins, Francis S.; Cox, Nancy J.; Goldstein, David B.; Hindorff, Lucia A.; Hunter, David J.; McCarthy, Mark I.; Ramos, Erin M.; Cardon, Lon R.; Chakravarti, Aravinda; Cho, Judy H.; Guttmacher, Alan E.; Kong, Augustine; Kruglyak, Leonid; Mardis, Elaine; Rotimi, Charles N.; Slatkin, Montgomery; Valle, David; Whittemore, Alice S.; Boehnke, Michael; Clark, Andrew G.; Eichler, Evan E.; Gibson, Greg; Haines, Jonathan L.; Mackay, Trudy F. C.; McCarroll, Steven A.; Visscher, Peter M. (2009). "Finding the missing heritability of complex diseases". Nature. 461 (7265): 747–753. Bibcode:2009Natur.461..747M. doi:10.1038/nature08494. ISSN 0028-0836. PMC 2831613. PMID 19812666.
15. Mackay, Trudy F. C.; Richards, Stephen; Stone, Eric A.; Barbadilla, Antonio; Ayroles, Julien F.; Zhu, Dianhui; Casillas, Sònia; Han, Yi; Magwire, Michael M.; Cridland, Julie M.; Richardson, Mark F.; et al. (2012). "The Drosophila melanogaster Genetic Reference Panel". Nature. 482 (7384): 173–178. Bibcode:2012Natur.482..173M. doi:10.1038/nature10811. ISSN 0028-0836. PMC 3683990. PMID 22318601.
16. "Trudy Mackay CV" (PDF). mackay.gnets.ncsu.edu.
17. ^ Anon (2006). "Professor Trudy Mackay FRS". royalsociety.org. London: Royal Society. Archived from the original on 2015-11-17. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --"Royal Society Terms, conditions and policies". Archived from the original on 2016-11-11. Retrieved 2016-03-09.{{cite web}}: CS1 maint: bot: original URL status unknown (link)

18. Falconer, Douglas; Mackay, Trudy F. C. (1996). Introduction to quantitative genetics (4th ed.). Essex, England: Longman. ISBN 9780582243026. OCLC 34415160.
19. Weir, Bruce (2004). "The 2004 Genetics Society of America Medal Trudy F. C. Mackay". Genetics. 166 (2): 647–648. doi:10.1534/genetics.166.2.647. PMC 1470721. PMID 15020454.
20. "The American Philosophical Society Welcomes New Members for 2021". American Philosophical Society. Retrieved 2021-05-12.
21. "Ground-breaking geneticist, Trudy Mackay, to receive prestigious Dawson Prize". EurekAlert!. Retrieved 2021-05-12.
22. "Fellows of AAAS" (PDF).
23. "Trudy F.C. Mackay". American Academy of Arts & Sciences. Retrieved 2021-05-12.

• 1952 births
• Living people
• Female fellows of the Royal Society
• Wolf Prize in Agriculture laureates
• People from Moncton
• Scottish geneticists
• British women geneticists
• Alumni of the University of Edinburgh
• North Carolina State University faculty
• Canadian women geneticists
• Canadian geneticists
• Fellows of the Royal Society
• Members of the United States National Academy of Sciences
• Fellows of the American Association for the Advancement of Science
• Clemson University faculty
• Biologists from South Carolina
• 21st-century Scottish women scientists
• 21st-century Scottish scientists
• Scottish women academics