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UBXD2

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Protein-coding gene in the species Homo sapiens

UBXN4
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2KXJ

Identifiers
AliasesUBXN4, UBXD2, UBXDC1, erasin, UBX domain protein 4
External IDsOMIM: 611216; MGI: 1915062; HomoloGene: 40962; GeneCards: UBXN4; OMA:UBXN4 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)
Chromosome 2 (human)Genomic location for UBXN4Genomic location for UBXN4
Band2q21.3Start135,741,734 bp
End135,785,056 bp
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)
Chromosome 1 (mouse)Genomic location for UBXN4Genomic location for UBXN4
Band1|1 E3Start128,171,701 bp
End128,207,115 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sperm

  • pylorus

  • cardia

  • secondary oocyte

  • optic nerve

  • seminal vesicula

  • body of pancreas

  • nipple

  • endometrium

  • corpus epididymis
Top expressed in
  • lacrimal gland

  • Rostral migratory stream

  • left lobe of liver

  • tail of embryo

  • supraoptic nucleus

  • prostate

  • salivary gland

  • lobe of prostate

  • seminal vesicula

  • retinal pigment epithelium
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

23190

67812

Ensembl

ENSG00000144224

ENSMUSG00000026353

UniProt

Q92575

Q8VCH8

RefSeq (mRNA)

NM_014607

NM_026390
NM_001356529

RefSeq (protein)

NP_055422

NP_080666
NP_001343458

Location (UCSC)Chr 2: 135.74 – 135.79 MbChr 1: 128.17 – 128.21 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

UBX domain-containing protein 4 is a protein that in humans is encoded by the UBXN4 gene.


References

  1. ^ GRCh38: Ensembl release 89: ENSG00000144224Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000026353Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Liang J, Yin C, Doong H, Fang S, Peterhoff C, Nixon RA, Monteiro MJ (Sep 2006). "Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation". J Cell Sci. 119 (Pt 19): 4011–24. doi:10.1242/jcs.03163. PMID 16968747. S2CID 1194226.
  6. "Entrez Gene: UBXD2 UBX domain containing 2".

Further reading

PDB gallery
  • 2dzk: Structure of the UBX domain in Mouse UBX Domain-Containing Protein 2 2dzk: Structure of the UBX domain in Mouse UBX Domain-Containing Protein 2


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