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This victory came during the greatest period of success in the history of the club, largely under coach Vujadin Boškov and featuring players such as Pagliuca, Mancini, Vialli, Vierchowod and Lombardo. In the 1988–89 Cup Winners' Cup they had finished runners-up to FC Barcelona in the Bern final, but in the same season won the Coppa Italia (one of four domestic cup wins from six finals in nine years), allowing another opportunity to compete for the European prize, which they duly achieved the following year. In the 1994–95 edition of the same tournament, Samp reached the semi-final before being eliminated on penalties by Arsenal.
In addition, Sampdoria won their only Serie A national title in 1991, and in the subsequent European Cup campaign they went all the way to the final in London, again facing Barcelona and losing by a single goal late in extra time. It was the last year before that competition became known as the Champions League, although its format did involve a group stage.
Since the mid-1990s, the club's European involvement has been less frequent and less prominent, although they have participated in the group stages of the UEFA Cup / Europa League on three occasions in the early 21st century (failing to progress each time).