Uusitalo is a Finnish surname. Notable people with the surname include:
- Eino Uusitalo (1924–2015), Finnish politician
- Arja Uusitalo (born 1951), Finnish poet and journalist
- Sami Uusitalo (born 1977), Finnish bass guitarist
- Ville Uusitalo (born 1979), Finnish professional ice hockey defenceman
- Markus Uusitalo (born 1997), Finnish professional footballer
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