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VMP1
Identifiers
Aliases	VMP1, EPG3, TANGO5, TMEM49, vacuole membrane protein 1
External IDs	OMIM: 611753; MGI: 1923159; HomoloGene: 23686; GeneCards: VMP1; OMA:VMP1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q23.1 Start 59,707,192 bp End 59,842,255 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 C Start 86,474,691 bp End 86,574,662 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood monocyte epithelium of colon gallbladder rectum mucosa of urinary bladder islet of Langerhans pericardium upper lobe of left lung appendix Top expressed in epithelium of small intestine stroma of bone marrow gastrula lobe of prostate jejunum yolk sac ileum duodenum decidua lacrimal gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component vacuolar membrane integral component of membrane vacuole plasma membrane autophagosome membrane nucleolus endoplasmic reticulum membrane phagophore assembly site endoplasmic reticulum-Golgi intermediate compartment membrane Biological process autophagy cell adhesion Golgi organization embryo implantation endoplasmic reticulum organization exocytosis cell junction assembly cell-cell adhesion autophagosome assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81671 75909 Ensembl ENSG00000062716 ENSMUSG00000018171 UniProt Q96GC9 Q99KU0 RefSeq (mRNA) NM_001329394 NM_001329395 NM_001329396 NM_001329397 NM_001329398 NM_001329399 NM_001329400 NM_001329401 NM_001329402 NM_030938 NM_029478 NM_001356531 NM_001379040 NM_001379041 RefSeq (protein) NP_001316323 NP_001316324 NP_001316325 NP_001316326 NP_001316327 NP_001316328 NP_001316329 NP_001316330 NP_001316331 NP_112200 NP_083754 NP_001343460 NP_001365969 NP_001365970 Location (UCSC) Chr 17: 59.71 – 59.84 Mb Chr 11: 86.47 – 86.57 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Vacuole membrane protein 1 is a protein that in humans is encoded by the VMP1 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000062716 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000018171 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
6. Dusetti NJ, Jiang Y, Vaccaro MI, Tomasini R, Azizi Samir A, Calvo EL, Ropolo A, Fiedler F, Mallo GV, Dagorn JC, Iovanna JL (Jan 2002). "Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation". Biochem Biophys Res Commun. 290 (2): 641–9. doi:10.1006/bbrc.2001.6244. PMID 11785947.
7. "VMP1 vacuole membrane protein 1 [ Homo sapiens (human) ]".

Further reading

• Ropolo A, Grasso D, Pardo R, et al. (2008). "The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells". J. Biol. Chem. 282 (51): 37124–33. doi:10.1074/jbc.M706956200. PMID 17940279.
• Sauermann M, Sahin O, Sültmann H, et al. (2008). "Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells". Oncogene. 27 (9): 1320–6. doi:10.1038/sj.onc.1210743. PMID 17724469. S2CID 1805602.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Starkuviene V, Liebel U, Simpson JC, et al. (2004). "High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic". Genome Res. 14 (10A): 1948–56. doi:10.1101/gr.2658304. PMC 524419. PMID 15466293.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

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