Vetrano is a surname. Notable people with the surname include:
- Candela Vetrano (born 1991), Argentine actress
- Giulia Vetrano (born 2005), Italian swimmer
- Joe Vetrano (1918–1995), American football player
- Karina Vetrano (1986–2016), American speech-language pathologist and murder victim
- Stefano Vetrano (1923–2018), Italian politician
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