VUK or Vuk may refer to:
- Vuk (computer), Yugoslavian computer prototype
- Vuk (film), an animated Hungarian movie
- Vuk (novel), a 1965 novel by Istvan Fekete
- Vuk (name), Slavic given name
- Vuk, Ban of Bosnia
- VUK-T (glider), often called VUK, a high-performance Yugoslavian sailplane
- Vojvoda Vuk, Chetnik voivoda (duke)
- Vuk Stefanović Karadžić (1787–1864), Serbian language reformer and folklorist, often referred to simply as Vuk
- Vuk., taxonomic author abbreviation for Ljudevit Vukotinović (1813–1893), Croatian naturalist
- Vukićević
- Volume Unique Key in the AACS, encryption system
- Value Up Kit
- Vuk, a character in the 2019 film Dark Phoenix
- Vertical up-kicker, a pinball part
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