Wang Kai may refer to:
- Wang Kai (actor): Chinese actor, also known as Nick Wang
- Wang Kai (Former Shu): Chancellor of Former Shu
- Wang Kai (footballer, born 1983): Chinese footballer
- Wang Kai (footballer, born 1989): Chinese footballer
- Wang Kai (Han dynasty) (王楷), an advisor to the Han dynasty warlord Lü Bu
- Wang Kai (born 1963): lieutenant general, the last commander of the former 13th Group Army, China
- Wang Kai (politician), governor of Henan
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