William Gosse may refer to:
- William Gosse (explorer) (1842-1881), Australian explorer
- William Gosse (surgeon), his father, medical practitioner in South Australia
- William Gosse (MP) for Bridgwater (UK Parliament constituency)
See also
- William Gosse Hay, brother-in-law and nephew of William Christie Gosse
- William Goss (disambiguation)
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