William Lucas or Bill Lucas may refer to:
- William Lucas (Virginia politician) (1800–1877), politician and lawyer from Virginia
- William Brooks Lucas, state legislator in the United States
- William V. Lucas (1835–1921), U.S. Republican politician representing South Dakota
- William Thomas Lucas (1875–1973), farmer and Canadian federal politician
- William Lucas (bishop) (1883–1945), inaugural Bishop of Masasi
- Bill Lucas (runner) (1917–2018), British long-distance runner
- Billy Lucas (1918–1998), Welsh footballer
- William R. Lucas (born 1922), fourth Director of the NASA Marshall Space Flight Center
- Bill Lucas (architect) (1924–2001), Australian architect
- William Lucas (actor) (1925–2016), British film and television actor
- William Lucas (Michigan politician) (1928–2022), Wayne County executive and 1986 Michigan gubernatorial candidate
- Bill Lucas (baseball) (1936–1979), American baseball executive
- Bill Lucas (rower) (born 1987), British rower
- Bill Lucas (academic) (born 1956), social entrepreneur, author, researcher and motivational speaker
- William Brooks Lucas, state legislature from Mississippi
- Bill Lucas (rugby league), Australian rugby league player
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