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Wolfgang Grodd | |
---|---|
Born | (1942-07-25) July 25, 1942 (age 82) Detmold |
Nationality | German |
Scientific career | |
Fields | Anatomy, MRI, Neuroradiology, Neurosciences |
Institutions | Max Planck Institute for Biological Cybernetics |
Wolfgang Grodd (born 25 July 1942 in Detmold) is a German neuroradiologist and professor emeritus of the University hospital at the University of Tübingen. He is known for his scientific works on the development and application of structural and functional magnetic resonance imaging in metabolic diseases, sensorimotor representation, language production, and cognitive processing, cerebellum, thalamus, and basal ganglia. Currently, Wolfgang Grodd is a research scientist at the Department of the High-Field MR at the Max Planck Institute for Biological Cybernetics.
Biography
After serving as a temporary soldier in the German Army from 1959 to 1964 and training as an electronics technician, W. Grodd obtained his Abitur (high school diploma) in 1968 at Westfalen Kolleg in Bielefeld and studied biology from 1968 to 1977 and medicine from 1974 to 1981 at the University of Tübingen. From 1972 to 1975 he was a scholarship holder of the Protestant Student Union Villigst. He received his diploma in biology in 1977 and his license to practice medicine in 1981. This was followed by residency training as a radiologist at the Medical Radiation Institute of the University of Tübingen (1981-1986), which was interrupted by a DFG research fellowship at the Department of Radiology at the University of San Francisco from 1984 to 1985.
In 1987, he initially moved to the Department of Neuroradiology at the University of Tübingen as a consultant, where he worked as a senior physician from 1991 to 1995. In 1991, he habilitated in the field of radiology/neuroradiology on the topic of experimental and clinical investigations of volume-selective proton spectroscopy of the human brain, and in the same year he was granted a teaching license in the field of neuroradiology. The following year, W. Grodd was appointed Professor of Neuroradiology at the Steglitz Clinic of the Free University of Berlin, but declined. From 1995, he was professor and head of the scientific section Experimental Nuclear Magnetic Resonance of the Central Nervous System at the University Hospital of Tübingen, where he gave his farewell lecture in 2010. Currently, Grodd is at the Department High-field Magnetic Resonance at the Max Planck Institute for Biological Cybernetics. He is ranked 463 globally and 33 in Germany in the 2023 Ranking of Best Scientists in Neuroscience (https://research.com/scientists-rankings/neuroscience). He has also been recognized with research.com’s “Neuroscience Leader Award for 2023” (https://research.com/u/wolfgang-grodd).
Scientific focus
- Clinical use of proton spectroscopy
- Maturation, abnormalities and metabolic diseases of children's brains
- Functional imaging of fear, sociopathy, humour and laughing
- Memory performance in Alzheimer's disease and dementia
- Language processing and speech production
- Functional anatomy of cerebellum and thalamus Using functional magnetic resonance imaging (fMRI), Grodd was able to demonstrate somatotopic activation areas for the motor activities of lips, tongue, hands and feet in the cortex of the cerebellum.
- Cognitive processing of visual processes
Awards
For his scientific research activity, Grodd was awarded the "Kurt-Decker Award" of the German Society for Neuroradiology in 1988, 1989, 1992 and in 1998. In 1989 the German Society for Neurotraumatology honored him for his outstanding scientific work.
Memberships in scientific organizations
Grodd is a member of various national and international scientific organizations:
- since 1988 International Society of Magnetic Resonance in Medicine(ISMRM)
- since 1988 European Society of Magnetic Resonance in Medicine and Biology (ESMRMB)
- since 1996 Organization for Human Brain Mapping(OHBM)
- since 1998 American Society of Advancement of Science(AAAS)
- since 2000 German Society of Clinical Neurophysiology(DGKN)
- since 2001 Society for Neuroscience(SNS)
Publications
Grodd is the author and co-author of over 250 publications in neuroscientific journals and 26 chapters in monographs and books.
References
- Grodd, W., Krägeloh-Mann, I., Petersen, D., Trefz, F.K., and Harzer, K. (1990). In vivo assessment of N-acetylaspartate in the brain in spongy degeneration (Canavan’s disease) by proton spectroscopy. Lancet 336, 437–438. PMID 1974962
- Grodd, W., Krägeloh-Mann, I., Klose, U., and Sauter, R. (1991). Metabolic and destructive brain disorders in children: findings with localized proton MR spectroscopy. Radiology 181, 173–181. PMID 1887030
- Grodd, W. (1993). Normal and abnormal patterns of myelin development of the fetal and infantile human brain using magnetic resonance imaging. Curr Opin Neurol Neurosurg 6, 393–397. PMID 8507909
- Staudt, M., Krägeloh-Mann, I., and Grodd, W. (2000). . Rofo 172, 802–811. PMID 11111291
- Wilke, M., Staudt, M., Juenger, H., Grodd, W., Braun, C., and Krägeloh-Mann, I. (2009). Somatosensory system in two types of motor reorganization in congenital hemiparesis: topography and function. Hum Brain Mapp 30, 776–788. PMID 18286510
- Eichler, F., Grodd, W., Grant, E., Sessa, M., Biffi, A., Bley, A., Kohlschuetter, A., Loes, D.J., and Kraegeloh-Mann, I. (2009). Metachromatic leukodystrophy: a scoring system for brain MR imaging observations. AJNR Am J Neuroradiol 30, 1893–1897. PMID 19797797
- Birbaumer, N., Veit, R., Lotze, M., Erb, M., Hermann, C., Grodd, W., and Flor, H. (2005). Deficient fear conditioning in psychopathy: a functional magnetic resonance imaging study. Arch. Gen. Psychiatry 62, 799–805. PMID 15997022
- Veit, R., Flor, H., Erb, M., Hermann, C., Lotze, M., Grodd, W., and Birbaumer, N. (2002). Brain circuits involved in emotional learning in antisocial behavior and social phobia in humans. Neurosci. Lett. 328, 233–236. PMID 12147314
- Wild, B., Rodden, F.A., Rapp, A., Erb, M., Grodd, W., and Ruch, W. (2006). Humor and smiling: cortical regions selective for cognitive, affective, and volitional components. Neurology 66, 887–893. PMID 16567707
- Wild, B., Rodden, F.A., Grodd, W., and Ruch, W. (2003). Neural correlates of laughter and humour. Brain 126, 2121–2138. PMID 12902310
- Heun, R., Klose, U., Jessen, F., Erb, M., Papassotiropoulos, A., Lotze, M., and Grodd, W. (1999). Functional MRI of cerebral activation during encoding and retrieval of words. Hum Brain Mapp 8, 157–169. PMID 10619411
- Heun, R., Freymann, K., Erb, M., Leube, D.T., Jessen, F., Kircher, T.T., and Grodd, W. (2007). Mild cognitive impairment (MCI) and actual retrieval performance affect cerebral activation in the elderly. Neurobiol. Aging 28, 404–413. PMID 16530885
- Heun, R., Jessen, F., Klose, U., Erb, M., Granath, D.-O., and Grodd, W. (2004). Response-related fMRI of veridical and false recognition of words. Eur. Psychiatry 19, 42–52. PMID 14969780
- Wildgruber, D., Ackermann, H., and Grodd, W. (2001). Differential contributions of motor cortex, basal ganglia, and cerebellum to speech motor control: effects of syllable repetition rate evaluated by fMRI. Neuroimage 13, 101–109. PMID 11133313
- Riecker, A., Ackermann, H., Wildgruber, D., Dogil, G., and Grodd, W. (2000). Opposite hemispheric lateralization effects during speaking and singing at motor cortex, insula and cerebellum. NeuroReport 11, 1997–2000. PMID 10884059
- Lidzba, K., Wilke, M., Staudt, M., Krägeloh-Mann, I., and Grodd, W. (2008). Reorganization of the cerebro-cerebellar network of language production in patients with congenital left-hemispheric brain lesions. Brain Lang 106, 204–210. PMID 18158178
- Brendel, B., Hertrich, I., Erb, M., Lindner, A., Riecker, A., Grodd, W., and Ackermann, H. (2010). The contribution of mesiofrontal cortex to the preparation and execution of repetitive syllable productions: an fMRI study. Neuroimage 50, 1219–1230. PMID 20080191
- Grodd, W., Hülsmann, E., and Ackermann, H. (2005). Functional MRI localizing in the cerebellum. Neurosurg. Clin. N. Am. 16, 77–99, v. PMID 15561530
- Sokolov, A.A., Erb, M., Grodd, W., and Pavlova, M.A. (2014). Structural loop between the cerebellum and the superior temporal sulcus: evidence from diffusion tensor imaging. Cereb. Cortex 24, 626–632. PMID 23169930
- Anders, S., Birbaumer, N., Sadowski, B., Erb, M., Mader, I., Grodd, W., and Lotze, M. (2004). Parietal somatosensory association cortex mediates affective blindsight. Nat. Neurosci. 7, 339–340. PMID 15034586
- Staudt, M., Gerloff, C., Grodd, W., Holthausen, H., Niemann, G., and Krägeloh-Mann, I. (2004). Reorganization in congenital hemiparesis acquired at different gestational ages. Ann. Neurol. 56, 854–863. PMID 15562409
- Lotze, M., Grodd, W., Birbaumer, N., Erb, M., Huse, E., and Flor, H. (1999). Does use of a myoelectric prosthesis prevent cortical reorganization and phantom limb pain? Nat. Neurosci. 2, 501–502. PMID 10448212
- Lotze M, Erb M, Flor H, Huelsmann E, Godde B, Grodd W (2000) fMRI evaluation of somatotopic representation in human primary motor cortex. Neuroimage 11:473-481. doi:10.1006/nimg.2000.0556
- Lotze M, Montoya P, Erb M, Hulsmann E, Flor H, Klose U, Birbaumer N, Grodd W (1999) Activation of cortical and cerebellar motor areas during executed and imagined hand movements: an fMRI study. J Cogn Neurosci 11:491-501. PMID 10511638
- Lotze M, Grodd W, Rodden FA, Gut E, Schönle PW, Kardatzki B, Cohen LG. Neuroimaging patterns associated with motor control in traumatic brain injury. Neurorehabil Neural Repair. 2006 Mar;20(1):14-23. PMID 16467275
- Kumar, V., Mang, S., and Grodd, W. (2014). Direct diffusion-based parcellation of the human thalamus. Brain Struct Funct 220, 1619–1635.^ PMID 24659254
- Mang, S.C., Busza, A., Reiterer, S., Grodd, W., Klose, and Uwe (2012). Thalamus segmentation based on the local diffusion direction: A group study. Magnetic Resonance in Medicine 67, 118–126. PMID 21656553
- Kourtzi, Z., Bülthoff, H.H., Erb, M., and Grodd, W. (2002). Object-selective responses in the human motion area MT/MST. Nat. Neurosci. 5, 17–18. PMID 11740503
- Bilalić, M., Turella, L., Campitelli, G., Erb, M., and Grodd, W. (2012). Expertise modulates the neural basis of context dependent recognition of objects and their relations. Hum. Brain Mapp. 33, 2728–2740. PMID 21998070
- Bilalić, M., Langner, R., Ulrich, R., and Grodd, W. (2011). Many faces of expertise: fusiform face area in chess experts and novices. J. Neurosci. 31, 10206–10214. PMID 21752997
- Bilalić, M., Langner, R., Campitelli, G., Turella, L., and Grodd, W. (2015). Editorial: Neural implementation of expertise. Front. Hum. Neurosci 545. PMID 26483662
- Chassy, P., and Grodd, W. (2012). Comparison of Quantities: Core and Format-Dependent Regions as Revealed by fMRI. Cereb. Cortex 22, 1420–1430. PMID 21878489
- Chassy, P., and Grodd, W. (2016). Editorial: Abstract Mathematical Cognition. Front. Hum. Neurosci 719. PMID 26858630
- German Society for Neuroradiology, Kurt-Decker Award
- Curriculum Vitae of Wolfgang Grodd, Max Planck Institute for Biological Cybernetics