Xaa-Pro aminopeptidase - Misplaced Pages

Xaa-Pro aminopeptidase (EC 3.4.11.9, X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, aminoacylproline aminopeptidase) is an enzyme. This enzyme catalyses the following chemical reaction

Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide

This enzyme is Mn-dependent.

References

Yaron A, Mlynar D (August 1968). "Aminopeptidase-P". Biochemical and Biophysical Research Communications. 32 (4): 658–63. doi:10.1016/0006-291x(68)90289-1. PMID 4878817.
Yaron, A.; Berger, A. (1970). Aminopeptidase-P. Methods Enzymol. Vol. 19. pp. 522–534. doi:10.1016/0076-6879(70)19039-2. ISBN 978-0-12-181881-4.
Fleminger G, Carmel A, Goldenberg D, Yaron A (July 1982). "Fluorogenic substrates for bacterial aminopeptidase P and its analogs detected in human serum and calf lung". European Journal of Biochemistry. 125 (3): 609–15. doi:10.1111/j.1432-1033.1982.tb06726.x. PMID 6749499.
Orawski AT, Susz JP, Simmons WH (June 1987). "Aminopeptidase P from bovine lung: solubilization, properties, and potential role in bradykinin degradation". Molecular and Cellular Biochemistry. 75 (2): 123–32. doi:10.1007/bf00229900. PMID 3627107. S2CID 37892547.
Hooper NM, Hryszko J, Turner AJ (April 1990). "Purification and characterization of pig kidney aminopeptidase P. A glycosyl-phosphatidylinositol-anchored ectoenzyme". The Biochemical Journal. 267 (2): 509–15. doi:10.1042/bj2670509. PMC 1131318. PMID 2139778.

External links

Xaa-Pro+aminopeptidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Hydrolase: proteases (EC 3.4)

3.4.11-19: Exopeptidase

3.4.11	Aminopeptidase Alanine Arginyl Aspartyl Cystinyl Leucyl Glutamyl Methionyl 1 2 O
3.4.13	Dipeptidase 1 2 3
3.4.14	Dipeptidyl peptidase Cathepsin C Dipeptidyl peptidase-4 Tripeptidyl peptidase Tripeptidyl peptidase I Tripeptidyl peptidase II
3.4.15	Angiotensin-converting enzyme
3.4.16	Serine type carboxypeptidases: Cathepsin A DD-Transpeptidase
3.4.17	Metalloexopeptidases Carboxypeptidase A A2 B C E Glutamate II
Other/ungrouped	Metalloexopeptidase

3.4.21-25: Endopeptidase

Other/ungrouped: Amyloid precursor protein secretase

3.4.99: Unknown

Staphylokinase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Portal:

Biology

Category:

EC 3.4.11