Zelikovitch (Hebrew: זליקוביץ׳, Yiddish: זעליקאָוויטש, Polish: Zelikowicz), also spelled Zelikovich or Zelikowitz, is an Ashkenazi Jewish surname. It is derived from the Yiddish-language personal name Zelig. The Slavic suffix "-ovich" means "son of".
The surname may refer to:
- Getzel Zelikovitch [he], Egyptologist, writer, journalist and translator
- Elimelekh Zelikovich [he], commander of the first instructors' course of the Hagana underground in the 1920s
- Reuven Zelicovici (later Rubin), Romanian-born Israeli painter and Israel's first ambassador to Romania
- Antonina Zelikovich, Russian rower
- Miriam Eshkol (née Zelikovich), wife of Israeli Prime Minister Levi Eshkol