Ziese is a surname. Notable people with the surname include:
- Burkhard Ziese (1944–2010), German football manager
- Carl H. Ziese (1848–1917), German mechanical engineer, railway machinery manufacturer and shipbuilder
- Christa Maria Ziese (1924–2012), German Lied, concert and operatic soprano
- Maxim Ziese (1901–1955), German dramatist and writer
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