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ZBED5
Identifiers
Aliases	ZBED5, Buster1, zinc finger BED-type containing 5
External IDs	OMIM: 615251; MGI: 1919220; HomoloGene: 84838; GeneCards: ZBED5; OMA:ZBED5 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.4 Start 10,812,074 bp End 10,858,796 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band 5|5 G1.3 Start 129,924,564 bp End 129,932,464 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibia epithelium of nasopharynx ganglionic eminence hair follicle left ovary skin of thigh body of uterus germinal epithelium ventricular zone right ovary Top expressed in Gonadal ridge otic vesicle zygote oocyte secondary oocyte spermatocyte primary oocyte medial ganglionic eminence cumulus cell embryo More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleoplasm cytoplasm Biological process regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 58486 71970 Ensembl ENSG00000236287 ENSMUSG00000034173 UniProt Q49AG3 n/a RefSeq (mRNA) NM_021211 NM_001143667 NM_183088 NM_001359408 RefSeq (protein) NP_001137139 NP_067034 n/a Location (UCSC) Chr 11: 10.81 – 10.86 Mb Chr 5: 129.92 – 129.93 Mb PubMed search
Wikidata
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Zinc finger BED-type containing 5 is a protein that in humans is encoded by the ZBED5 gene.

Function

This gene is unusual in that its coding sequence is mostly derived from Charlie-like DNA transposon; however, it does not appear to be an active DNA transposon as it is not flanked by terminal inverted repeats. The encoded protein is conserved among the mammalian Laurasiatheria branch. Multiple alternatively spliced variants, encoding the same protein, have been identified.

See also

• BED zinc finger

References

1. ^ GRCh38: Ensembl release 89: ENSG00000236287 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000034173 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Zinc finger BED-type containing 5". Retrieved 2016-11-07.

Further reading

• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.

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