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Robert H. Grubbs
Grubbs in 2018
Born	Robert Howard Grubbs (1942-02-27)February 27, 1942 Marshall County, Kentucky, U.S.
Died	December 19, 2021(2021-12-19) (aged 79) Duarte, California, U.S.
Education	University of Florida (BS, MS) Columbia University (PhD)
Known for	Catalysts for olefin metathesis in organic synthesis
Spouse	Helen O'Kane
Awards	Tolman Award (2002) Linus Pauling Award (2003) Nobel Prize in Chemistry (2005) AIC Gold Medal (2010) ForMemRS (2017)
Scientific career
Fields	Organic chemistry
Institutions	Stanford University Michigan State University California Institute of Technology
Thesis	I. Cyclobutadiene Derivatives II. Studies of Cyclooctatetraene Iron Tricarbonyl Complexes (1968)
Doctoral advisor	Ronald Breslow
Doctoral students	SonBinh Nguyen Melanie Sanford Timothy M. Swager
Other notable students	Post-docs: Steven Buchwald Sukbok Chang Geoffrey Coates Gregory Fu Jennifer Love Adam Matzger Dean Toste
Website	grubbsgroup.caltech.edu

Robert Howard Grubbs ForMemRS (February 27, 1942 – December 19, 2021) was an American chemist and the Victor and Elizabeth Atkins Professor of Chemistry at the California Institute of Technology in Pasadena, California. He was a co-recipient of the 2005 Nobel Prize in Chemistry for his work on olefin metathesis.

Grubbs was elected a member of the National Academy of Engineering in 2015 for developments in catalysts that have enabled commercial products.

He was a co-founder of Materia, a university spin-off startup to produce catalysts.

Early life and education

Grubbs was born on February 27, 1942, on a farm in Marshall County, Kentucky, midway between Possum Trot and Calvert City. His parents were Howard and Faye (Atwood) Grubbs. Faye was a schoolteacher. After serving in World War II, the family moved to Paducah, Kentucky, where Howard trained as a diesel mechanic, and Robert attended Paducah Tilghman High School.

At the University of Florida, Grubbs initially intended to study agriculture chemistry. However, he was convinced by professor Merle A. Battiste to switch to organic chemistry. Working with Battiste, he became interested in how chemical reactions occur. He received his B.S. in 1963 and M.S. in 1965 from the University of Florida.

Next, Grubbs attended Columbia University, where he worked with Ronald Breslow on organometallic compounds which contain carbon-metal bonds. Grubbs received his Ph.D. in 1968.

Career

Grubbs worked with James Collman at Stanford University as a National Institutes of Health fellow during 1968–1969. With Collman, he began to systematically investigate catalytic processes in organometallic chemistry, a then relatively new area of research.

In 1969, Grubbs was appointed to the faculty of Michigan State University, where he began his work on olefin metathesis. Harold Hart, Gerasimos J. Karabatsos, Gene LeGoff, Don Farnum, Bill Reusch and Pete Wagner served as his early mentors at MSU. Grubbs was an assistant professor from 1969 to 1973, and an associate professor from 1973 to 1978. He received a Sloan Fellowship for 1974–1976. In 1975, he went to the Max Planck Institute for Coal Research in Mülheim, Germany, on a fellowship from the Alexander von Humboldt Foundation.

In 1978, Grubbs moved to California Institute of Technology as a professor of chemistry. As of 1990 he became the Victor and Elizabeth Atkins Professor of Chemistry.

As of 2021, Grubbs has an h-index of 160 according to Google Scholar and of 137 according to Scopus.

Commercial activities

Both first and second generation Grubbs catalysts were commercially available from Materia, a startup company that Grubbs co-founded with Mike Giardello in Pasadena, California, in 1998. Materia has been able to obtain exclusive rights to manufacture many of the known olefin catalysts. Under Giardello, Materia was able to sell their catalysts through Sigma-Aldrich's chemicals catalogue. Sigma-Aldrich became their exclusive worldwide provider. In 2008, Materia partnered with Cargill to form Elevance Renewable Sciences to produce specialty chemicals from renewable oils, including biofuels. In 2017, Materia sold its catalyst business to Umicore. In 2021, Materia was acquired by ExxonMobil.

Grubbs was a member of the Reliance Innovation Council formed by Reliance Industries Limited, India.

Grubbs was a member of the USA Science and Engineering Festival's advisory board.

Research

Grubbs's main research interests were in organometallic chemistry and synthetic chemistry, particularly the development of novel catalysts for olefin metathesis. In olefin metathesis, a catalyst is used to break the bonds of carbon molecules, which can then re-form to create chemical bonds in new ways, producing new compounds with unique properties. The basic technique can be used for creation of polymers, pharmaceuticals and petrochemicals and has broad applications in areas including pharmaceuticals, biotechnology, agriculture, and plastics.

Grubbs was instrumental in developing a family of ruthenium catalysts, including Grubbs catalyst for olefin metathesis. He studied olefin transformations for ring-closing metathesis (RCM), cross-metathesis reaction (CMR), and ring-opening metathesis polymerization (ROMP) with cyclic olefins such as norbornene. He also contributed to the development of "living polymerization", in which the termination ability of a polymerization reaction is removed. The polymer will continue to replicate until a quenching agent is presented.

The Grubbs group successfully polymerized the 7-oxo norbornene derivative using ruthenium trichloride, osmium trichloride as well as tungsten alkylidenes. They identified a Ru(II) carbene as an effective metal center and in 1992 published the first well-defined, ruthenium-based olefin metathesis catalyst, (PPh₃)₂Cl₂Ru=CHCH=CPh₂.

The corresponding tricyclohexylphosphine complex (PCy₃)₂Cl₂Ru=CHCH=CPh₂ was also shown to be active. This work culminated in the now commercially available first-generation Grubbs catalyst in 1995. Second generation catalysts were developed as well.

Ruthenium is stable in air and has higher selectivity and lower reactivity than molybdenum, the most promising of the previously discovered catalysts. In addition, Grubbs took a green chemistry approach to catalysis that reduced the potential to create hazardous waste. The Grubbs catalyst has become a standard for general metathesis applications in ordinary laboratories.

By controlling the catalyst used, it became possible to synthesize polymers with specialized structures and functional capabilities, including cyclic olefins, alternating copolymers, and multiblock copolymers. Using catalysts allows chemists to speed up chemical transformations and to lower the cost of what were previously complicated multi-step industrial processes.

Personal life

While at Columbia University, Grubbs also met his future wife, Helen O'Kane, a special-education teacher, with whom he had three children: Barney (born 1972), Brendan H. (born 1974) and Kathleen (Katy) (born 1977).

Grubbs died from a heart attack at the City of Hope Comprehensive Cancer Center in Duarte, California, on December 19, 2021, at age 79. At the time of his death, he was being treated for lymphoma.

Awards and honors

Grubbs received the 2005 Nobel Prize in Chemistry, along with Richard R. Schrock and Yves Chauvin, for his work in the field of olefin metathesis. He has received a number of other awards and honors, including the following:

• 1989: National Academy of Sciences
• 1994: American Academy of Arts and Sciences
• 2000: Benjamin Franklin Medal in Chemistry from the Franklin Institute
• 2000: ACS Herman F. Mark Polymer Chemistry Award
• 2001: ACS Herbert C. Brown Award for Creative Research in Synthetic Methods
• 2002: Tolman Medal
• 2002: Arthur C. Cope Award
• 2003: Tetrahedron Prize for Creativity in Organic Chemistry & BioMedicinal Chemistry (with Dieter Seebach)
• 2005: Nobel Prize in Chemistry (with Richard R. Schrock and Yves Chauvin)
• 2005: Honorary Fellow of the Royal Society of Chemistry
• 2005: Paul Karrer Gold Medal
• 2006: Golden Plate Award of the American Academy of Achievement
• 2009: Fellow of the American Chemical Society
• 2010: American Institute of Chemists Gold Medal
• 2015: Inducted into the Florida Inventors Hall of Fame
• 2013: National Academy of Inventors
• 2015: National Academy of Engineering
• 2015: Chinese Academy of Sciences (foreign academician)
• 2017: Ira Remsen Award
• 2017: Elected a Foreign Member of the Royal Society

Publications

• Grubbs, Robert (2003). Handbook of Metathesis. Weinheim, Germany; Chichester, England: Wiley-VCH John Wiley distributor. ISBN 978-3-527-30616-9. OCLC 52485738.

References

1. ^ Anon (2017). "Professor Robert Grubbs ForMemRS". royalsociety.org. London: Royal Society.
2. ^ Grubbs, Robert Howard (1968). I. Cyclebutadiene Derivatives II. Studies of Cyclooctatetraene Iron Tricarbonyl Complexes (PhD thesis). Columbia University. ProQuest 302317287. (subscription required)
3. Nguyen, SonBinh TheBao (1995). The designs, syntheses, and applications of well-defined, single component group VIII olefin metathesis catalysts (phd). California Institute of Technology. doi:10.7907/1BVB-S189. Retrieved December 20, 2021. Research Advisor(s): Grubbs, Robert H.
4. Sanford, Melanie Sarah (2001). Synthetic and mechanistic investigations of ruthenium olefin metathesis catalysts (phd). California Institute of Technology. doi:10.7907/Q96P-VK05. Retrieved December 20, 2021. Research Advisor(s): Grubbs, Robert H.
5. "People – The Sanford Group". WordPress Websites – Offered by LSA Technology Services. October 29, 2021. Retrieved December 20, 2021.
6. Swager, Timothy Manning (1988). Precursor Routes to Conducting Polymers from the Ring-Opening Metathesis Polymerization of Cyclic Olefins (phd). California Institute of Technology. doi:10.7907/KF6P-FC76. Retrieved December 20, 2021. Research Advisor(s): Grubbs, Robert H.
7. ^ "American Institute of Chemists Gold Medal". Science History Institute. March 22, 2018.
8. ^ "Press Release, 5 October 2005". The Nobel Prize in Chemistry 2005. NobelPrize.org. Retrieved April 12, 2016.
9. "Lanxess rubber employs Materia catalysts". Chemical & Engineering News. 84 (34): 23. August 21, 2006. Retrieved January 9, 2018.
10. ^ "Jackson Purchase Nobel Laureate". Jackson Purchase Historical Society. Retrieved April 12, 2016.
11. ^ "Robert H. Grubbs – Biographical". The Nobel Prize in Chemistry 2005. NobelPrize.org. Retrieved April 12, 2016. In some places, my birthplace is listed as Calvert City and in others Possum Trot. I was actually born between the two, so either one really is correct.
12. History and Families, McCracken County, Kentucky, 1824–1989. Turner Publishing Company. December 22, 1989. ISBN 9780938021360. Retrieved December 22, 2021 – via Google Books.
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14. ^ Janine Young, Sikes (October 6, 2005). "A Gator wins Nobel in chemistry". The Gainesville Sun. Archived from the original on April 21, 2016. Retrieved April 14, 2016.
15. Doerfler, Andrew (December 20, 2021). "UF Mourns the Passing of Robert H. Grubbs, Nobel-Winning Alumnus". News – College of Liberal Arts & Sciences. Retrieved December 22, 2021.
16. "Robert H. Grubbs PhD " Leadership Board". Department of Chemistry, University of Florida. Retrieved April 14, 2016.
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19. "Robert H. Grubbs American chemist". Encyclopædia Britannica. April 26, 2024.
20. ^ "2002 Robert H. Grubbs, Caltech". Southern California Section of the American Chemical Society. July 20, 2012. Retrieved April 12, 2016.
21. Robert H. Grubbs publications indexed by Google Scholar
22. Robert H. Grubbs publications indexed by the Scopus bibliographic database. (subscription required)
23. ^ Notman, Nina (January 28, 2015). "Grubbs catalyst". Chemistry World. Retrieved April 15, 2016.
24. ^ "Industry's Secret Ingredient". Caltech News. Archived from the original on September 10, 2015. Retrieved April 17, 2014.
25. "Leading Innovation in Catalysis". Materia. Retrieved April 15, 2016.
26. "The History of Materia". Materia. Retrieved April 15, 2016.
27. "Materia and Sigma-Aldrich Announce Exclusive Distribution Deal for Grubbs' Metathesis Catalysts". Business Wire. August 18, 2003. Retrieved April 15, 2016.
28. Tullo, Alexander H. (March 31, 2008). "Cargill, Materia Launch New Firm Elevance will make specialty chemicals from vegetable oils". Chemical & Engineering News. 86 (13): 6. doi:10.1021/cen-v086n013.p006.
29. Kotrba, Ron (March 23, 2010). "Newton plant to become biorefinery showcase". Biodiesel Magazine. Retrieved April 15, 2016.
30. "Materia, Inc. Sells Catalyst Business to Umicore". Materia. December 20, 2017. Retrieved June 10, 2021.
31. "ExxonMobil acquires Materia, Inc., a high-performance structural polymers company". ExxonMobil. Retrieved December 18, 2021.
32. "Reliance Innovation Council (2007–2017) – Raghunath Mashelkar – Mukesh Ambani – Jean-Marie Lehn – Robert Grubbs – George Whitesides – Gary Hamel – William Haseltine". Reliance Industries Limited. Archived from the original on December 16, 2021. Retrieved December 20, 2021.
33. "Nobel Laureates". USA Science & Engineering Festival. Archived from the original on April 21, 2010. Retrieved April 12, 2016.
34. ^ Miree-Luke, Lisa (October 8, 2015). "Axalta's Distinguished Lecture Series at the University of Pennsylvania Features Presentation on Methathesis Polymerization". Business Wire. Retrieved April 14, 2016.
35. ^ Pearson, Rodney (April 3, 2001). "South Pasadena chemist wins national award for designing new catalysts". EurekaAlert. Archived from the original on April 15, 2016. Retrieved April 14, 2016.
36. ^ Singh, Okram Mukherjee (2006). "Metathesis catalysts: Historical perspective, recent developments and practical applications" (PDF). Journal of Scientific & Industrial Research. 65 (December): 957–965. Retrieved April 12, 2016.
37. Grubbs, Robert H. (2006). "Olefin-Metathesis Catalysts for the Preparation of Molecules and Materials (Nobel Lecture)". Angewandte Chemie International Edition. 45 (23): 3760–3765. doi:10.1002/anie.200600680. PMID 16724297.
38. Chatterjee, Arnab K.; Choi, Tae-Lim; Sanders, Daniel P.; Grubbs, Robert H. (September 2003). "A General Model for Selectivity in Olefin Cross Metathesis" (PDF). Journal of the American Chemical Society. 125 (37): 11360–11370. Bibcode:2003JAChS.12511360C. doi:10.1021/ja0214882. PMID 16220959. Retrieved April 14, 2016.
39. ^ Nguyen, SonBinh T.; Johnson, Lynda K.; Grubbs, Robert H.; Ziller, Joseph W. (May 1992). "Ring-opening metathesis polymerization (ROMP) of norbornene by a Group VIII carbene complex in protic media" (PDF). Journal of the American Chemical Society. 114 (10): 3974–3975. Bibcode:1992JAChS.114.3974N. doi:10.1021/ja00036a053.
40. Schrock, R. R.; Feldman, J.; Cannizzo, L. F.; Grubbs, R. H. (September 1987). "Ring-opening polymerization of norbornene by a living tungsten alkylidene complex". Macromolecules. 20 (5): 1169–1172. Bibcode:1987MaMol..20.1169S. doi:10.1021/ma00171a053.
41. Novak, Bruce M.; Grubbs, Robert H. (1988). "The ring opening metathesis polymerization of 7-oxabicyclohept-5-ene derivatives: a new acyclic polymeric ionophore". Journal of the American Chemical Society. 110 (3): 960–961. Bibcode:1988JAChS.110..960N. doi:10.1021/ja00211a043.
42. Nguyen, Sonbinh T.; Grubbs, Robert H.; Ziller, Joseph W. (1993). "Syntheses and activities of new single-component, ruthenium-based olefin metathesis catalysts". Journal of the American Chemical Society. 115 (21): 9858–9859. Bibcode:1993JAChS.115.9858N. doi:10.1021/ja00074a086.
43. Schwab, Peter; France, Marcia B.; Ziller, Joseph W.; Grubbs, Robert H. (1995). "A Series of Well-Defined Metathesis Catalysts–Synthesis of and Its Reactions". Angew. Chem. Int. Ed. Engl. 34 (18): 2039–2041. doi:10.1002/anie.199520391.
44. Schwab, Peter; Grubbs, Robert H.; Ziller, Joseph W. (1996). "Synthesis and Applications of RuCl₂(=CHR')(PR₃)₂: The Influence of the Alkylidene Moiety on Metathesis Activity". Journal of the American Chemical Society. 118 (1): 100–110. Bibcode:1996JAChS.118..100S. doi:10.1021/ja952676d.
45. ^ Astruc, Didier (2005). "The metathesis reactions: from a historical perspective to recent developments" (PDF). New Journal of Chemistry. 29 (1): 42. doi:10.1039/b412198h. Archived from the original (PDF) on June 16, 2016. Retrieved April 12, 2016.
46. Wilson, Gerald O.; Porter, Keith A.; Weissman, Haim; White, Scott R.; Sottos, Nancy R.; Moore, Jeffrey S. (August 14, 2009). "Stability of Second Generation Grubbs' Alkylidenes to Primary Amines: Formation of Novel Ruthenium-Amine Complexes". Advanced Synthesis & Catalysis. 351 (11–12): 1817–1825. doi:10.1002/adsc.200900134.
47. "Columbia News ::: Alumnus Robert Grubbs Wins Nobel Prize in Chemistry". www.columbia.edu. Archived from the original on March 1, 2017. Retrieved July 21, 2016.
48. ^ McClain, Dylan Loeb (December 24, 2021). "Robert H. Grubbs, 79, Dies; Chemistry Breakthrough Led to a Nobel". The New York Times. Retrieved December 24, 2021.
49. "Caltech Mourns the Loss of Nobel Laureate Robert H. Grubbs". Caltech. December 19, 2021. Retrieved December 19, 2021.
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54. "Herman F. Mark Award 2000". Division of Polymer Chemistry, Inc. of the American Chemical Society. Archived from the original on March 15, 2016. Retrieved April 14, 2016.
55. "Pasadena chemist wins national award for cata". EurekAlert!. Retrieved December 20, 2021.
56. "Arthur C. Cope Award". ACS Chemistry for Life. American Chemical Society. Retrieved April 12, 2016.
57. "Tetrahedron Prize for Creativity". Elsevier B.V. Retrieved April 12, 2016.
58. "Members Grubbs". rsc.org. Royal Society of Chemistry. Retrieved April 15, 2016.
59. "Robert H. Grubbs 31st Paul Karrer Lecture 2005". University of Zurich. Archived from the original on April 23, 2016. Retrieved April 12, 2016.
60. "Golden Plate Awardees of the American Academy of Achievement". www.achievement.org. American Academy of Achievement.
61. "2009 ACS Fellows". American Chemical Society. Archived from the original on February 24, 2019. Retrieved April 15, 2016.
62. "2015 Inductees: Robert Howard Grubbs". Florida Inventors Hall of Fame. September 28, 2015. Retrieved April 14, 2016.
63. "Current NAI Fellows". National Academy of Inventors. Retrieved April 15, 2016.
64. "Professor Robert Howard Grubbs". National Academy of Engineering. Retrieved April 12, 2016.
65. "New Academicians and Foreign Members of the Chinese Academy of Sciences". Angewandte Chemie International Edition. 55 (8): 2633–2634. February 2016. doi:10.1002/anie.201511637.
66. "12 Famous Scientists Elected 2015 CAS Foreign Members". CASAD. Retrieved April 12, 2016.
67. Wang, Linda (February 13, 2017). "Robert Grubbs wins Remsen Award". Chemical & Engineering News. 59 (7). American Chemical Society. Retrieved December 20, 2021.

External links

• "Press Release, 5 October 2005". The Nobel Prize in Chemistry 2005. NobelPrize.org.
• Robert H. Grubbs on Nobelprize.org

v t e Laureates of the Nobel Prize in Chemistry
1901–1925	1901: Jacobus van 't Hoff 1902: Emil Fischer 1903: Svante Arrhenius 1904: William Ramsay 1905: Adolf von Baeyer 1906: Henri Moissan 1907: Eduard Buchner 1908: Ernest Rutherford 1909: Wilhelm Ostwald 1910: Otto Wallach 1911: Marie Curie 1912: Victor Grignard / Paul Sabatier 1913: Alfred Werner 1914: Theodore Richards 1915: Richard Willstätter 1916 1917 1918: Fritz Haber 1919 1920: Walther Nernst 1921: Frederick Soddy 1922: Francis Aston 1923: Fritz Pregl 1924 1925: Richard Zsigmondy
1926–1950	1926: Theodor Svedberg 1927: Heinrich Wieland 1928: Adolf Windaus 1929: Arthur Harden / Hans von Euler-Chelpin 1930: Hans Fischer 1931: Carl Bosch / Friedrich Bergius 1932: Irving Langmuir 1933 1934: Harold Urey 1935: Frédéric Joliot-Curie / Irène Joliot-Curie 1936: Peter Debye 1937: Norman Haworth / Paul Karrer 1938: Richard Kuhn 1939: Adolf Butenandt / Leopold Ružička 1940 1941 1942 1943: George de Hevesy 1944: Otto Hahn 1945: Artturi Virtanen 1946: James B. Sumner / John Northrop / Wendell Meredith Stanley 1947: Robert Robinson 1948: Arne Tiselius 1949: William Giauque 1950: Otto Diels / Kurt Alder
1951–1975	1951: Edwin McMillan / Glenn T. Seaborg 1952: Archer Martin / Richard Synge 1953: Hermann Staudinger 1954: Linus Pauling 1955: Vincent du Vigneaud 1956: Cyril Hinshelwood / Nikolay Semyonov 1957: Alexander Todd 1958: Frederick Sanger 1959: Jaroslav Heyrovský 1960: Willard Libby 1961: Melvin Calvin 1962: Max Perutz / John Kendrew 1963: Karl Ziegler / Giulio Natta 1964: Dorothy Hodgkin 1965: Robert Woodward 1966: Robert S. Mulliken 1967: Manfred Eigen / Ronald Norrish / George Porter 1968: Lars Onsager 1969: Derek Barton / Odd Hassel 1970: Luis Federico Leloir 1971: Gerhard Herzberg 1972: Christian B. Anfinsen / Stanford Moore / William Stein 1973: Ernst Otto Fischer / Geoffrey Wilkinson 1974: Paul Flory 1975: John Cornforth / Vladimir Prelog
1976–2000	1976: William Lipscomb 1977: Ilya Prigogine 1978: Peter D. Mitchell 1979: Herbert C. Brown / Georg Wittig 1980: Paul Berg / Walter Gilbert / Frederick Sanger 1981: Kenichi Fukui / Roald Hoffmann 1982: Aaron Klug 1983: Henry Taube 1984: Robert Merrifield 1985: Herbert A. Hauptman / Jerome Karle 1986: Dudley R. Herschbach / Yuan T. Lee / John Polanyi 1987: Donald J. Cram / Jean-Marie Lehn / Charles J. Pedersen 1988: Johann Deisenhofer / Robert Huber / Hartmut Michel 1989: Sidney Altman / Thomas Cech 1990: Elias Corey 1991: Richard R. Ernst 1992: Rudolph A. Marcus 1993: Kary Mullis / Michael Smith 1994: George Olah 1995: Paul J. Crutzen / Mario Molina / F. Sherwood Rowland 1996: Robert Curl / Harold Kroto / Richard Smalley 1997: Paul D. Boyer / John E. Walker / Jens Christian Skou 1998: Walter Kohn / John Pople 1999: Ahmed Zewail 2000: Alan J. Heeger / Alan MacDiarmid / Hideki Shirakawa
2001–present	2001: William Knowles / Ryoji Noyori / K. Barry Sharpless 2002: John B. Fenn / Koichi Tanaka / Kurt Wüthrich 2003: Peter Agre / Roderick MacKinnon 2004: Aaron Ciechanover / Avram Hershko / Irwin Rose 2005: Robert H. Grubbs / Richard R. Schrock / Yves Chauvin 2006: Roger D. Kornberg 2007: Gerhard Ertl 2008: Osamu Shimomura / Martin Chalfie / Roger Y. Tsien 2009: Venkatraman Ramakrishnan / Thomas A. Steitz / Ada E. Yonath 2010: Richard F. Heck / Akira Suzuki / Ei-ichi Negishi 2011: Dan Shechtman 2012: Robert Lefkowitz / Brian Kobilka 2013: Martin Karplus / Michael Levitt / Arieh Warshel 2014: Eric Betzig / Stefan Hell / William E. Moerner 2015: Tomas Lindahl / Paul L. Modrich / Aziz Sancar 2016: Jean-Pierre Sauvage / Fraser Stoddart / Ben Feringa 2017: Jacques Dubochet / Joachim Frank / Richard Henderson 2018: Frances Arnold / Gregory Winter / George Smith 2019: John B. Goodenough / M. Stanley Whittingham / Akira Yoshino 2020: Emmanuelle Charpentier / Jennifer Doudna 2021: David MacMillan / Benjamin List 2022: Carolyn R. Bertozzi / Morten P. Meldal / Karl Barry Sharpless 2023: Moungi G. Bawendi / Louis E. Brus / Alexei I. Ekimov 2024: David Baker / Demis Hassabis / John M. Jumper

• 1942 births
• 2021 deaths
• 20th-century American chemists
• 21st-century American chemists
• American Nobel laureates
• California Institute of Technology faculty
• Columbia University alumni
• Members of the United States National Academy of Sciences
• Members of the United States National Academy of Engineering
• Foreign members of the Chinese Academy of Sciences
• Foreign members of the Royal Society
• Fellows of the Royal Society of Chemistry
• Michigan State University faculty
• Nobel laureates in Chemistry
• Paducah Tilghman High School alumni
• People from Marshall County, Kentucky
• People from Paducah, Kentucky
• University of Florida College of Liberal Arts and Sciences alumni
• Benjamin Franklin Medal (Franklin Institute) laureates