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| ==Presentation== | ==Presentation== | ||
| Complex partial seizures are often preceded by a ] ].<ref name="Trescher, William H. 1749">Trescher, William H., and Ronald P. Lescher 2000, p. 1749.</ref> The seizure aura is a ].<ref name="Trescher, William H. 1749"/> |
Complex partial seizures are often preceded by a ] ].<ref name="Trescher, William H. 1749">Trescher, William H., and Ronald P. Lescher 2000, p. 1749.</ref> The seizure aura is a ].<ref name="Trescher, William H. 1749"/> It ] might occur as a feeling of ], ], fear, ], or ].<ref name="Murro, Anthony M. 2006">Murro, Anthony M. 2006.</ref> The seizure ] might also occur as a visual disturbance, such as ] or a change in the size of objects (] or ]).<ref> Engelsen, B A., C Tzoulis, B Karlsen, A Lillebø, L M 2008.</ref> Once consciousness is impaired, the person may display ]s such as lip smacking, chewing, or swallowing.<ref name="Murro, Anthony M. 2006"/> There may also be loss of memory (]) surrounding the seizure event.<ref name="Trescher, William H. 1749"/> The person may still be able to perform routine tasks such as walking or shopping. Witnesses may not recognize that anything is wrong. | ||
| Complex partial seizures might arise from any ] of the brain.<ref name="Trescher, William H. 1749"/> Complex partial seizures most commonly arise from the ] ], particularly the ], ] and ] regions.<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1750.</ref> A common associated brain abnormality is ].<ref name="Murro, Anthony M. 2006"/> Mesial temporal sclerosis is a specific pattern of hippocampal neuronal loss accompanied by hippocampal gliosis and atrophy.<ref>Trepeta, Scott 2007.</ref> Complex partial seizures occur when excessive and synchronous electrical brain activity causes impaired awareness and responsiveness.<ref>"International League Against Epilepsy." 2008.</ref> The abnormal electrical activity might spread to the rest of the brain and cause a secondary generalized ].<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1747.</ref> | Complex partial seizures might arise from any ] of the brain.<ref name="Trescher, William H. 1749"/> Complex partial seizures most commonly arise from the ] ], particularly the ], ] and ] regions.<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1750.</ref> A common associated brain abnormality is ].<ref name="Murro, Anthony M. 2006"/> Mesial temporal sclerosis is a specific pattern of hippocampal neuronal loss accompanied by hippocampal gliosis and atrophy.<ref>Trepeta, Scott 2007.</ref> Complex partial seizures occur when excessive and synchronous electrical brain activity causes impaired awareness and responsiveness.<ref>"International League Against Epilepsy." 2008.</ref> The abnormal electrical activity might spread to the rest of the brain and cause a secondary generalized ].<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1747.</ref> | ||
Revision as of 20:59, 7 December 2008
Medical condition| Complex partial seizure | |
|---|---|
| Specialty | Neurology  |
A complex partial seizure is an epileptic seizure that is limited to one cerebral hemisphere and causes impairment of awareness or responsiveness.
Presentation
Complex partial seizures are often preceded by a seizure aura. The seizure aura is a simple partial seizure. It aura might occur as a feeling of déjà vu, jamais vu, fear, euphoria, or depersonalization. The seizure aura might also occur as a visual disturbance, such as tunnel vision or a change in the size of objects (macropsia or micropsia). Once consciousness is impaired, the person may display automatisms such as lip smacking, chewing, or swallowing. There may also be loss of memory (amnesia) surrounding the seizure event. The person may still be able to perform routine tasks such as walking or shopping. Witnesses may not recognize that anything is wrong.
Complex partial seizures might arise from any lobe of the brain. Complex partial seizures most commonly arise from the mesial temporal lobe, particularly the amygdala, hippocampus and neocortical regions. A common associated brain abnormality is mesial temporal sclerosis. Mesial temporal sclerosis is a specific pattern of hippocampal neuronal loss accompanied by hippocampal gliosis and atrophy. Complex partial seizures occur when excessive and synchronous electrical brain activity causes impaired awareness and responsiveness. The abnormal electrical activity might spread to the rest of the brain and cause a secondary generalized tonic-clonic seizure.
Creativity & Epilepsy
Some observations suggest that complex partial seizures might enhance creativity. However, research studies have generated conflicting results. In 2002, researchers at the Guelhane Military Medical Academy in Turkey evaluated thirty men with epilepsy and thirty-six men without. The men were instructed to use fragmented parts of a drawing to create a picture of their own. Those with complex partial seizures scored higher than their counterparts. A 2004 study suggested that temporal lobe epilepsy was not associated with their measure of creativity.
Complex partial seizures and religious hallucinations
Though her supporters disagree, the founder of the Seventh-day Adventist Church, Ellen G. White's visions of God may have been caused by partial seizures. She had previously lost consciousness from a head injury. Her brain injury was significant enough to prevent her return to school.
See also
Notes
- Trescher, William H., and Ronald P. Lescher 2000, p. 1748.
- ^ Trescher, William H., and Ronald P. Lescher 2000, p. 1749.
- ^ Murro, Anthony M. 2006.
- Engelsen, B A., C Tzoulis, B Karlsen, A Lillebø, L M 2008.
- Trescher, William H., and Ronald P. Lescher 2000, p. 1750.
- Trepeta, Scott 2007.
- "International League Against Epilepsy." 2008.
- Trescher, William H., and Ronald P. Lescher 2000, p. 1747.
- Natalie Angier: In the Temporal Lobes, Seizures and Creativity. New York Times, October 12, 1993.
- E. Togrol, A. Togrol, S. Can: Creative thinking in epilepsy. Boğaziçi University, 2002.
- Temporal lobe Epilepsy and Creativity: A Model of Association
- The Ellen White Research Project
References
- Engelsen, B A., C Tzoulis, B Karlsen, A Lillebø, L M. Laegreid, J Aasly, M Zeviani, and L A. Bindoff. "POLG1 Mutations Cause a Syndromic Epilepsy with Occipital Lobe Predilection." Brain 131 (2008): 818-828.
- "International League Against Epilepsy." 2008. International League Against Epilepsy. Accessed 9 Apr. 2008 <http://www.ilae-epilepsy.org/>.
- Murro, Anthony M. "eMedicine - Complex Partial Seizures." 11 Oct. 2006. Medical College of Georgia. Accessed 9 Apr. 2008 <http://www.emedicine.com/neuro/topic74.htm>.
- Natalie Angier: In the Temporal Lobes, Seizures and Creativity. New York Times, October 12, 1993.
- Togrol E., Togrol A., S. Can: Creative thinking in epilepsy. Boğaziçi University, 2002.
- Trepeta, Scott. "eMedicine - Mesial Temporal Sclerosis." 11 Sept. 2007. Jamaica Hospital. Accessed 9 Apr. 2008 <http://www.emedicine.com/radio/topic443.htm>.
- Trescher, William H., and Ronald P. Lescher. "The Epilepsies." Neurology in Clinical Practice. Ed. Walter G. Bradley, Robert B. Daroff, Gerald M. Fenichel, and C. David Marsden. Boston: Butterworth-Heinemann, 2000. 1745-1780.
- Epilepsy Action - Link Between Complex Partial Epilepsy and Creativity
- Temporal Lobe Epilepsy and Creativity: A Model of Association
- Old Testament prophet showed epileptic symptoms
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