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'''Polycaprolactone''' ('''PCL''') is a ] ] with a low ] of around 60°C and a ] of about −60°C. PCL can be prepared by ] of ] using a ] such as stannous octanoate. '''Polycaprolactone''' ('''PCL''') is a ] ] with a low ] of around 60°C and a ] to lower its cost and increase biodegradability or it can be added as a polymeric ] to ].

]

This polymer is often used as an additive for resins to improve their processing characteristics and their end use properties (e.g.: ] resistance). Being compatible with a range of other materials, PCL can be mixed with ] to lower its cost and increase biodegradability or it can be added as a polymeric ] to ].


Polycaprolactone is also used for splinting, modelling, and as a ] for prototype ] systems such as ]. Polycaprolactone is also used for splinting, modelling, and as a ] for prototype ] systems such as ].


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== Biomedical Applications ==

PCL is degraded by ] of its ] linkages in physiological conditions (such as in the human body) and has therefore received a great deal of attention for use as an implantable ]. In particular it is especially interesting for the preparation of long term implantable devices, owing to its degradation which is even slower than that of ].

PCL is an ] (FDA) approved material that is used in the human body as (for example) a drug delivery device, ], ] barrier and is being investigated as a scaffold for tissue repair via ].

A variety of drugs have been encapsulated within PCL beads for controlled release and targeted drug delivery which have been peer reviewed.
==External links==
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Revision as of 11:46, 8 July 2006

Polycaprolactone (PCL) is a biodegradable polyester with a low melting point of around 60°C and a [[glass transition temperah starch to lower its cost and increase biodegradability or it can be added as a polymeric plasticizer to PVC.

Polycaprolactone is also used for splinting, modelling, and as a feedstock for prototype Fused Deposition Modeling systems such as RepRap.

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