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The 1968 Harelbeke–Antwerp–Harelbeke was the 11th edition of the E3 Harelbeke cycle race and was held on 23 March 1968. The race started and finished in Harelbeke. The race was won by Jaak De Boever.
The race was known as Harelbeke–Antwerp–Harelbeke (French: Harelbeke–Anvers–Harelbeke) for the first twelve editions. In 1970, the race became known as the E3, after the Belgian road which is now known as the E17.