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2,4-Dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase (EC 2.4.1.202, uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase, BX8, BX9, benzoxazinoid glucosyltransferase, DIMBOA glucosyltransferase) is an enzyme with systematic name UDP-alpha-D-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-beta-D-glucosyltransferase. This enzyme catalyses the following chemical reaction

(1) UDP-alpha-D-glucose + 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one ${\displaystyle \rightleftharpoons }$ UDP + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside

(2) UDP-alpha-D-glucose + 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one ${\displaystyle \rightleftharpoons }$ UDP + (2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside

The enzyme is involved in the detoxification of the benzoxazinoids, DIBOA (2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one) and DIMBOA (2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one).

References

1. Bailey BA, Larson RL (July 1989). "Hydroxamic Acid glucosyltransferases from maize seedlings". Plant Physiology. 90 (3): 1071–6. doi:10.1104/pp.90.3.1071. PMC 1061845. PMID 16666853.
2. von Rad U, Hüttl R, Lottspeich F, Gierl A, Frey M (December 2001). "Two glucosyltransferases are involved in detoxification of benzoxazinoids in maize". The Plant Journal. 28 (6): 633–42. doi:10.1046/j.1365-313x.2001.01161.x. PMID 11851909.

External links

• 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one+2-D-glucosyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

• EC 2.4.1