Alcian yellow
Names
IUPAC name
{(E )-1,2-Diazenediylbis}bis
Other names
Ingrain Yellow 1
Identifiers
CAS Number
3D model (JSmol )
ChEBI
ChemSpider
ECHA InfoCard
100.115.894
PubChem CID
InChI
InChI=1S/C40H46N8S4/c1-25-19-35-33(21-29(25)23-49-39(45(3)4)46(5)6)41-37(51-35)27-11-15-31(16-12-27)43-44-32-17-13-28(14-18-32)38-42-34-22-30(26(2)20-36(34)52-38)24-50-40(47(7)8)48(9)10/h11-22H,23-24H2,1-10H3/q+2/b44-43+Key: QMKQNEXRGZFFKQ-VGFSZAGXSA-N InChI=1/C40H46N8S4/c1-25-19-35-33(21-29(25)23-49-39(45(3)4)46(5)6)41-37(51-35)27-11-15-31(16-12-27)43-44-32-17-13-28(14-18-32)38-42-34-22-30(26(2)20-36(34)52-38)24-50-40(47(7)8)48(9)10/h11-22H,23-24H2,1-10H3/q+2/b44-43+Key: QMKQNEXRGZFFKQ-VGFSZAGXBQ
SMILES
Cc1cc2c(cc1CSC(=(C)C)N(C)C)nc(s2)c3ccc(cc3)/N=N/c4ccc(cc4)c5nc6cc(c(cc6s5)C)CSC(=(C)C)N(C)C
Properties
Chemical formula
C40 H46 N8 S4
Molar mass
767.11 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
Infobox references
Chemical compound
Alcian yellow is an azo dye with the formula (CH3 2 C6 H2 SNCC6 H4 )2 N2 . Its structure consists of a largely conjugated array of benzene , benzothiazole and isothiouronium units.
Histological Use
Alcian yellow is used in histology in conjunction with toluidine blue to help visualize H. pylori . The resulting structures are stained as follows:
– Mucin : yellow
– H. pylori: blue
– Other cellular components/background: shades of blue
See also
References
Leung, Jennifer K.; Gibbon, Kevin J.; Vartanian, Robert K. (1996-06-01). "Rapid Staining Method for Helicobacter Pylori in Gastric Biopsies". Journal of Histotechnology . 19 (2): 131–132. doi :10.1179/his.1996.19.2.131 . ISSN 0147-8885 .
"Helico*Stat Rapid Helicobacter Stain Kit Procedure" (PDF). Archived from the original (PDF) on 2017-03-06. Retrieved 2017-03-05.
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