DPU may refer to:
Universities
- Dalian Polytechnic University, in Liaoning, China
- Danube Private University, in Krems an der Donau, Austria
- DePaul University, in Chicago, Illinois
- DePauw University, in Greencastle, Indiana
- Dhurakij Pundit University, in Bangkok, Thailand
- Dumlupınar University, in Turkey
Other uses
- Data processing unit, a type of specialized computer hardware
- Delayed pressure urticaria
- Depleted uranium
- Dinosaur Pile-Up, an English alternative rock band
- 1,3-Diphenylurea, a type of plant hormone
- Distributed power unit, in rail transport
- Massachusetts Department of Public Utilities
- Delivered at place unloaded, an international trade term
- Diphu railway station, a train station in Diphu, Assam, India
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