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ERGIC3
Identifiers
Aliases	ERGIC3, C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84, dJ477O4.2, ERGIC and golgi 3, C2orf47
External IDs	OMIM: 616971; MGI: 1913616; HomoloGene: 5289; GeneCards: ERGIC3; OMA:ERGIC3 - orthologs
Gene location (Human) Chr. Chromosome 20 (human) Band 20q11.22 Start 35,542,038 bp End 35,557,634 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2 H1|2 77.32 cM Start 155,849,965 bp End 155,860,199 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube right testis left testis stromal cell of endometrium olfactory zone of nasal mucosa right lobe of thyroid gland left lobe of thyroid gland canal of the cervix mucosa of transverse colon left ovary Top expressed in molar neural layer of retina yolk sac choroid plexus of fourth ventricle right kidney dentate gyrus of hippocampal formation granule cell external carotid artery vestibular sensory epithelium epithelium of lens tail of embryo More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 51614 66366 Ensembl ENSG00000125991 ENSMUSG00000005881 UniProt Q9Y282 Q9CQE7 RefSeq (mRNA) NM_015966 NM_198398 NM_025516 NM_001356413 NM_001356414 RefSeq (protein) NP_057050 NP_938408 NP_079792 NP_001343342 NP_001343343 Location (UCSC) Chr 20: 35.54 – 35.56 Mb Chr 2: 155.85 – 155.86 Mb PubMed search
Wikidata
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Endoplasmic reticulum-Golgi intermediate compartment protein 3 is a protein that in humans is encoded by the ERGIC3 gene. It has been reported to be regulated by micro RNAs and may be important in a cancer.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000125991 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000005881 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
6. "Entrez Gene: ERGIC3 ERGIC and golgi 3".
7. Zhang, Ling-yun; Liu, Min; Li, Xin; Tang, Hua (2013). "miR-490-3p Modulates Cell Growth and Epithelial to Mesenchymal Transition of Hepatocellular Carcinoma Cells by Targeting Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 3 (ERGIC3)". Journal of Biological Chemistry. 288 (6): 4035–4047. doi:10.1074/jbc.M112.410506. ISSN 0021-9258. PMC 3567655. PMID 23212913.
8. Lin, Qing-Hai; Zhang, Kui-Dong; Duan, He-Xian; Liu, Min-Xia; Wei, Wan-Li; Cao, Yi (2015). "ERGIC3, which is regulated by miR-203a, is a potential biomarker for non-small cell lung cancer". Cancer Science. 106 (10): 1463–1473. doi:10.1111/cas.12741. ISSN 1347-9032. PMC 4638005. PMID 26177443.

Further reading

• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scanlan MJ, Gout I, Gordon CM, et al. (2003). "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression". Cancer Immun. 1: 4. PMID 12747765.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. 279 (45): 47242–53. doi:10.1074/jbc.M406644200. PMID 15308636.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Nishikawa M, Kira Y, Yabunaka Y, Inoue M (2007). "Identification and characterization of endoplasmic reticulum-associated protein, ERp43". Gene. 386 (1–2): 42–51. doi:10.1016/j.gene.2006.06.030. PMID 17020792.

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