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Eberconazole

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Chemical compound Pharmaceutical compound
Eberconazole
Clinical data
Trade namesEbernet
Legal status
Legal status
  • US: Not FDA approved
Identifiers
IUPAC name
  • 1-(1,3-Dichloro-6,11-dihydro-5H-dibenzo annulen-11-yl)imidazole
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H14Cl2N2
Molar mass329.22 g·mol
3D model (JSmol)
SMILES
  • C1CC2=CC(=CC(=C2C(C3=CC=CC=C31)N4C=CN=C4)Cl)Cl
InChI
  • InChI=1S/C18H14Cl2N2/c19-14-9-13-6-5-12-3-1-2-4-15(12)18(17(13)16(20)10-14)22-8-7-21-11-22/h1-4,7-11,18H,5-6H2
  • Key:MPTJIDOGFUQSQH-UHFFFAOYSA-N

Eberconazole is an antifungal drug. As a 1% topical cream, it is an effective treatment for dermatophytosis, candidiasis, and pityriasis.

It was approved for use in Spain in 2015 and is sold under the trade name Ebernet. It is also approved for use in Panama, Guatemala, Costa Rica, Honduras, and the Dominican Republic.

References

  1. ^ "Ebernet". NewBridge Pharmaceuticals. Archived from the original on 2016-04-24. Retrieved 2017-01-15.
  2. del Palacio A, Ortiz FJ, Pérez A, Pazos C, Garau M, Font E (2001). "A double-blind randomized comparative trial: eberconazole 1% cream versus clotrimazole 1% cream twice daily in Candida and dermatophyte skin infections". Mycoses. 44 (5): 173–80. doi:10.1046/j.1439-0507.2001.00632.x. PMID 11486455.
  3. Repiso Montero T, López S, Rodríguez C, del Rio R, Badell A, Gratacós MR (May 2006). "Eberconazole 1% cream is an effective and safe alternative for dermatophytosis treatment: multicenter, randomized, double-blind, comparative trial with miconazole 2% cream". International Journal of Dermatology. 45 (5): 600–4. doi:10.1111/j.1365-4632.2006.02841.x. PMID 16700802.
  4. "Eberconazole". Drugs.com. Archived from the original on 2021-01-17. Retrieved 2017-01-15.
Antifungals (D01 and J02)
Wall/
membrane
Ergosterol
inhibitors
Azoles (lanosterol 14α-
demethylase
inhibitors)
Imidazoles
  • Systemic: ketoconazole
Triazoles
Thiazoles
Polyene antimycotics
(ergosterol binding)
Squalene monooxygenase
inhibitors
Allylamines
Benzylamines
Others
β-glucan synthase
inhibitors
Intracellular
Pyrimidine analogues/
thymidylate synthase inhibitors
Mitotic inhibitors
Aminoacyl tRNA synthetase inhibitors
Others


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