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Fructose-6-phosphate phosphoketolase

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fructose-6-phosphate phosphoketolase
Identifiers
EC no.4.1.2.22
CAS no.37290-57-6
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The enzyme fructose-6-phosphate phosphoketolase (EC 4.1.2.22) catalyzes the chemical reaction

D-fructose 6-phosphate + phosphate {\displaystyle \rightleftharpoons } acetyl phosphate + D-erythrose 4-phosphate + H2O

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming). Other names in common use include D-fructose-6-phosphate D-erythrose-4-phosphate-lyase, and (phosphate-acetylating). This enzyme participates in pentose phosphate pathway.

References

  • Schramm M, Klybas V, Racker E (1958). "Phospholytic cleavage of fructose-6-phosphate by fructose-6-phosphate phosphoketolase from Acetobacter xylinum". J. Biol. Chem. 233: 1283–1288.
Carbon–carbon lyases (EC 4.1)
4.1.1: Carboxy-lyases
4.1.2: Aldehyde-lyases
4.1.3: Oxo-acid-lyases
4.1.99: Other
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