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Hydroxypyruvate isomerase

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hydroxypyruvate isomerase
Identifiers
EC no.5.3.1.22
CAS no.74812-48-9
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In enzymology, a hydroxypyruvate isomerase (EC 5.3.1.22) is an enzyme that catalyzes the chemical reaction

hydroxypyruvate {\displaystyle \rightleftharpoons } 2-hydroxy-3-oxopropanoate

Hence, this enzyme has one substrate, hydroxypyruvate, and one product, 2-hydroxy-3-oxopropanoate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is hydroxypyruvate aldose-ketose-isomerase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

  • de Windt FE, van der Drift C (1980). "Purification and some properties of hydroxypyruvate isomerase of Bacillus fastidiosus". Biochim. Biophys. Acta. 613 (2): 556–62. doi:10.1016/0005-2744(80)90111-4. PMID 7448201.
Isomerases: intramolecular oxidoreductases (EC 5.3)
5.3.1: Aldoses/Ketoses
5.3.2: Keto/Enol
5.3.3: C = C
5.3.4: S-S
5.3.99: other
Enzymes
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