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Kitasamycin

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Chemical compound

Pharmaceutical compound
Kitasamycin
Clinical data
Other namesTurimycin
AHFS/Drugs.comInternational Drug Names
ATCvet code
Identifiers
IUPAC name
  • oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde (non-preferred name)
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC35H59NO13
Molar mass701.851 gยทmol
3D model (JSmol)
SMILES
  • C1C/C=C/C=C/((C((((CC(=O)O1)O)OC)O2((((O2)C)O3C(((O3)C)O)(C)O)N(C)C)O)CC=O)C)O
InChI
  • InChI=1S/C35H59NO13/c1-19-16-23(14-15-37)31(32(44-8)25(39)17-26(40)45-20(2)12-10-9-11-13-24(19)38)49-34-29(41)28(36(6)7)30(21(3)47-34)48-27-18-35(5,43)33(42)22(4)46-27/h9-11,13,15,19-25,27-34,38-39,41-43H,12,14,16-18H2,1-8H3/b10-9+,13-11+/t19-,20-,21-,22+,23+,24+,25-,27+,28-,29-,30-,31+,32+,33+,34+,35-/m1/s1
  • Key:XYJOGTQLTFNMQG-KJHBSLKPSA-N
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Kitasamycin (INN) is a macrolide antibiotic. It is produced by Streptomyces kitasatoensis. The drug has antimicrobial activity against a wide spectrum of pathogens. There are several generic names of this drug such as:

  • Kitasamycin (OS: BAN, JAN, USAN)
  • Kitasamycine (OS: DCF)
  • C 637 (IS)
  • Katasamycin (IS)
  • Leucomycin (IS)
  • Kitasamycin (PH: JP XV)
  • Kitasamycin Acetate (OS: JAN)
  • Leucomycin Acetate (IS)
  • Kitasamycin Acetate (PH: JP XV)
  • Kitasamycin Tartrate (OS: JAN)
  • Leucomycin Tartrate (IS)
  • Kitasamycin Tartrate (PH: JP XV)

References

  1. Zheng Q, Gao S (November 2016). "The effect of surfactant on fermentation of kitasamycin in Streptomyces kitasatoensis". Biotechnology and Applied Biochemistry. 63 (6): 895โ€“900. doi:10.1002/bab.1443. PMID 26339801. S2CID 7290695.
  2. "Kitasamycin". Drugs.com. Archived from the original on 20 October 2012.


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Antibacterials that inhibit protein synthesis (J01A, J01B, J01F, J01G, QJ01XQ)
30S
Aminoglycosides
(initiation inhibitors)
-mycin (Streptomyces)
-micin (Micromonospora)
other
Tetracycline antibiotics
(tRNA binding)
Tetracyclines
Glycylcyclines
50S
Oxazolidinone
(initiation inhibitors)
Peptidyl transferase
Amphenicols
MLS (transpeptidation/translocation)
Macrolides
Ketolides
Lincosamides
Streptogramins
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