Lopa may refer to:
- LoPa, common abbreviation for Finnish football club Lohjan Pallo
- LOPA (Layers of protection analysis), a risk management technique
- Lopa (fly), a genus in family Coelopidae
- Lopa County, in Imatong State, South Sudan
- Lopa language, a Kainji language spoken in Nigeria
People
- Baharuddin Lopa (1935–2001), Indonesian minister and attorney general
- Dmytro Lopa (born 1988), Ukrainian football midfielder
- Lopa Patel, British digital entrepreneur
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