N4-Chloroacetylcytosine arabinoside

N-Chloroacetylcytosine arabinoside
Names

IUPAC name N--2-chloroacetamide
Systematic IUPAC name 2-Chloro-N-{1--2-oxo-1,2-dihydropyrimidin-4-yl}acetamide
Identifiers
CAS Number	113737-52-3
3D model (JSmol)	Interactive image
ChemSpider	2338731
PubChem CID	3081042
CompTox Dashboard (EPA)	DTXSID00921180
InChI InChI=1S/C11H14ClN3O6/c12-3-7(17)13-6-1-2-15(11(20)14-6)10-9(19)8(18)5(4-16)21-10/h1-2,5,8-10,16,18-19H,3-4H2,(H,13,14,17,20)/t5-,8-,9+,10-/m1/s1Key: WEJWVQRPBCYTRE-STRWAFKBSA-N InChI=1/C11H14ClN3O6/c12-3-7(17)13-6-1-2-15(11(20)14-6)10-9(19)8(18)5(4-16)21-10/h1-2,5,8-10,16,18-19H,3-4H2,(H,13,14,17,20)/t5-,8-,9+,10-/m1/s1Key: WEJWVQRPBCYTRE-STRWAFKBBD
SMILES c1cn(c(=O)nc1NC(=O)CCl)2(((O2)CO)O)O
Properties
Chemical formula	C₁₁H₁₄ClN₃O₆
Molar mass	319.70 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references

Chemical compound

N-Chloroacetylcytosine arabinoside is a GABA agonist and might be a pro-drug for cytosine arabinoside, a chemotherapy medication.

References

Li, S; Zhang, Y; Liu, H; Yan, Y; Li, Y (2008). "Identification and expression of GABAC receptor in rat testis and spermatozoa". Acta Biochimica et Biophysica Sinica. 40 (8): 761–7. doi:10.1111/j.1745-7270.2008.00453.x. PMID 18685793.
M, Ariatti; PA, Jones. "N4-chloroacetylcytosine arabinoside--a possible pro-drug of cytosine arabinoside". Biochemistry international. 15 (6). Biochem Int. ISSN 0158-5231. PMID 3440022. Retrieved 2024-11-05.

GABA_ATooltip γ-Aminobutyric acid A receptor

GABA_A-ρTooltip γ-Aminobutyric acid A-rho receptor

GABA_BTooltip γ-Aminobutyric acid B receptor

See also: Receptor/signaling modulators; GABA_A receptor positive modulators; GABA metabolism/transport modulators

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