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Aceburic acid

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Chemical compound Pharmaceutical compound
Aceburic acid
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 4-(Acetyloxy)butanoic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC6H10O4
Molar mass146.142 g·mol
3D model (JSmol)
SMILES
  • CC(=O)OCCCC(=O)O
InChI
  • InChI=1S/C6H10O4/c1-5(7)10-4-2-3-6(8)9/h2-4H2,1H3,(H,8,9)
  • Key:GOVNVPJYMDJYSR-UHFFFAOYSA-N
  (what is this?)  (verify)

Aceburic acid (INN), also known as 4-acetoxybutanoic acid or 4-hydroxybutyric acid acetate, is a drug described as an analgesic which was never marketed. It is the acetyl ester of gamma-hydroxybutyrate (GHB, which is 4-hydroxybutanoic acid), and based on its structural relation to GHB, is likely to behave as a prodrug to it.

See also

References

  1. ^ Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1052–. ISBN 978-0-412-46630-4.
  2. Dardoize F, Goasdoue C, Goasdoue N, Laborit HM, Topall G (1989-01-01). "4-Hydroxybutyric acid (and analogues) derivatives of D-glucosamine". Tetrahedron. 45 (24): 7783–7794. doi:10.1016/S0040-4020(01)85793-8. ISSN 0040-4020.


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GABA receptor modulators
Ionotropic
GABAATooltip γ-Aminobutyric acid A receptor
GABAATooltip γ-Aminobutyric acid A-rho receptor
Metabotropic
GABABTooltip γ-Aminobutyric acid B receptor
See also
Receptor/signaling modulators
GABAA receptor positive modulators
GABA metabolism/transport modulators
GHB receptor modulators
Receptor
(ligands)
GHBRTooltip GHB receptor
GABABTooltip γ-Aminobutyric acid B receptor
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(blockers)
MCTsTooltip Monocarboxylate transporters
SMCTsTooltip Sodium-coupled monocarboxylate transporters
VIATTTooltip Vesicular inhibitory amino acid transporter
Enzyme
(inhibitors)
SSRTooltip Succinic semialdehyde reductase
GHBDHTooltip 4-Hydroxybutyrate dehydrogenase
HOTTooltip Hydroxyacid-oxoacid transhydrogenase
ADHTooltip Alcohol dehydrogenase
ALDHTooltip Aldehyde dehydrogenase
See also
Receptor/signaling modulators
GABA receptor modulators
Glutamate receptor modulators
Glycine receptor modulators


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