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Pelvic venous disease
Other names	Pelvic congestion syndrome, Pelvic venous insufficiency, Pelvic varicocele syndrome
A very large (9 cm) fibroid of the uterus which is causing pelvic congestion syndrome as seen on X-ray computed tomography
Specialty	Interventional Radiology, gynecology
Symptoms	Chronic pelvic pain, lower back pain, leg pain, dyspareunia, dysmenorrhea
Complications	Chronic pain, varicose veins in lower extremities, mood disturbances
Usual onset	Typically premenopausal women, often after multiple pregnancies
Duration	Chronic
Types	Primary (due to vein insufficiency) and Secondary (due to external compression)
Causes	Hormonal influences, vein valve dysfunction, increased pelvic blood flow from pregnancy
Risk factors	Multiple pregnancies, hormonal imbalances, family history, varicose veins
Diagnostic method	Ultrasound, CT scan, MRI, Pelvic venography, Laparoscopy
Differential diagnosis	Endometriosis, Irritable Bowel Syndrome, Interstitial Cystitis
Prevention	None specific, but early diagnosis and management are beneficial
Treatment	Hormonal therapy, Ovarian vein embolization, Sclerotherapy, pain management, compression garments
Medication	Medroxyprogesterone, Nonsteroidal anti-inflammatory drugs (NSAIDs), Gonadotropin-releasing hormone agonists
Prognosis	Often favorable with treatment; ~70-80% symptom relief post-embolization
Frequency	30% of women presenting complaints of chronic pelvic pain
Deaths	Rare

Pelvic congestion syndrome, also known as pelvic vein incompetence, is a long-term condition believed to be due to enlarged veins in the lower abdomen. The condition may cause chronic pain, such as a constant dull ache, which can be worsened by standing or sex. Pain in the legs or lower back may also occur.

While the condition is believed to be due to blood flowing back into pelvic veins as a result of faulty valves in the veins, this hypothesis is not certain. The condition may occur or worsen during pregnancy. The presence of estrogen is believed to be involved in the mechanism. Diagnosis may be supported by ultrasound, CT scan, MRI, or laparoscopy.

Early treatment options include medroxyprogesterone or nonsteroidal anti-inflammatory drugs (NSAIDs). Surgery to block the varicose veins may also be done. About 30% of women of reproductive age are affected. It is believed to be the cause of about a third of chronic pelvic pain cases. While pelvic venous insufficiency was identified in the 1850s it was only linked with pelvic pain in the 1940s.

Signs and symptoms

Women with this condition experience a constant pain that may be dull and aching, but is occasionally more acute. The pain is worse at the end of the day and after long periods of standing, and those affected get relief when they lie down. The pain is worse during or after sexual intercourse, and can be worse just before the onset of the menstrual period.

Women with pelvic congestion syndrome have a larger uterus and a thicker endometrium. 56% of women manifest cystic changes to the ovaries, and many report other symptoms, such as dysmenorrhea, back pain, vaginal discharge, abdominal bloating, mood swings or depression, and fatigue.

Causes

1. Local pelvic hormonal milieu
2. Venous outflow obstruction, such as May-Thurner syndrome, Nutcracker syndrome, Budd-Chiari syndrome, or left renal vein thrombosis
3. External compression due to tumor (including fibroids, endometriosis), or scarring

Diagnosis

Diagnosis can be made using ultrasound or laparoscopy testing. The condition can also be diagnosed with a venogram, CT scan, or an MRI. Ultrasound is the diagnostic tool most commonly used. Some research has suggested that transvaginal duplex ultrasound is the best test for pelvic venous reflux.

Treatment

Early treatment options include pain medication using nonsteroidal anti-inflammatory drugs, and suppression of ovarian function.

More advanced treatment includes a minimally invasive procedure performed by an Interventional Radiologist. This minimally invasive procedure involves stopping blood within the pelvic varicose veins using a minimally invasive procedure called a catheter directed embolization. The procedure rarely requires an overnight stay in hospital and is usually performed as an outpatient procedure, and is done using local anesthetic and moderate sedation. Patients report an 80% success rate, as measured by the amount of pain reduction experienced.

See also

• Ovarian vein syndrome
• Nutcracker syndrome
• May-Thurner syndrome
• Budd-Chiari syndrome

References

1. ^ "Pelvic Congestion Syndrome - Women's Health Issues". Merck Manuals Consumer Version. Retrieved 27 September 2019.
2. "Pelvic Congestion Syndrome: Causes, Symptoms & Treatment". Cleveland Clinic. 2023. Retrieved October 29, 2024.
3. "Pelvic Congestion Syndrome". Radiopaedia. Retrieved October 29, 2024.
4. ^ "Pelvic Pain (Pelvic Congestion Syndrome)". Johns Hopkins Medicine. Archived from the original on December 7, 2010. Retrieved December 23, 2010.
5. ^ Brown, CL; Rizer, M; Alexander, R; Sharpe EE, 3rd; Rochon, PJ (March 2018). "Pelvic Congestion Syndrome: Systematic Review of Treatment Success". Seminars in Interventional Radiology. 35 (1): 35–40. doi:10.1055/s-0038-1636519. PMC 5886772. PMID 29628614.{{cite journal}}: CS1 maint: numeric names: authors list (link)
6. ^ Cheema, Omer Saadat; Singh, Pramvir (2020). "Pelvic Congestion Syndrome". Statpearls. PMID 32809625. Text was copied from this source, which is available under a Creative Commons Attribution 4.0 International License.
7. ^ Champaneria, R; Shah, L; Moss, J; Gupta, JK; Birch, J; Middleton, LJ; Daniels, JP (January 2016). "The relationship between pelvic vein incompetence and chronic pelvic pain in women: systematic reviews of diagnosis and treatment effectiveness". Health Technology Assessment. 20 (5): 1–108. doi:10.3310/hta20050. PMC 4781546. PMID 26789334.
8. ^ "Dysmenorrhea". Merck Online Medical Manual. December 2008. Retrieved December 23, 2010.
9. ^ Phillip Reginald, MD. "Pelvic Congestion". The International Pelvic Pain Society. Archived from the original (PDF) on September 16, 2014. Retrieved December 23, 2010.
10. Rutherford's vascular surgery references. : Elsevier Saunders. 2014. ISBN 978-0323243056.
11. Whiteley M, Dos Santos S, Harrison C, Holdstock J, Lopez A (Oct 2014). "Transvaginal duplex ultrasonography appears to be the gold standard investigation for the haemodynamic evaluation of pelvic venous reflux in the ovarian and internal iliac veins in women". Phlebology. 30 (10): 706–13. doi:10.1177/0268355514554638. PMID 25324278. S2CID 25053851.

External links

• Sexual health
• Noninflammatory disorders of female genital tract
• Syndromes in females
• Syndromes affecting the vascular system