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Scytalidopepsin A (EC 3.4.23.31, Scytalidium aspartic proteinase A, Scytalidium lignicolum aspartic proteinase, Scytalidium lignicolum aspartic proteinase A-2, Scytalidium lignicolum aspartic proteinase A-I, Scytalidium lignicolum aspartic proteinase C, Scytalidium lignicolum carboxyl proteinase, Scytalidium lignicolum acid proteinase) is an enzyme. This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with specificity similar to that of pepsin A, but also cleaves Cys(SO₃H)-Gly and Leu-Val in the B chain of insulin

This enzyme is isolated from the fungus Scytalidium lignicolum.

References

1. Oda K, Murao S (1974). "Purification and some enzymatic properties of acid protease A and B of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 38: 2435–2444. doi:10.1271/bbb1961.38.2435.
2. Oda K, Murao S (1976). "Action of Scytalidium lignicolum acid proteases on insulin B-chain". Agric. Biol. Chem. 40: 1221–1225. doi:10.1271/bbb1961.40.1221.
3. Oda K, Torishima H, Murao S (1986). "Purification and characterization of acid proteinase C of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 50: 651–658. doi:10.1271/bbb1961.50.651.

External links

• Scytalidopepsin+A at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

• EC 3.4.23