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Sphingosine beta-galactosyltransferase

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Class of enzymes
sphingosine beta-galactosyltransferase
Identifiers
EC no.2.4.1.23
CAS no.9032-90-0
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In enzymology, a sphingosine beta-galactosyltransferase (EC 2.4.1.23) is an enzyme that catalyzes the chemical reaction

UDP-galactose + sphingosine {\displaystyle \rightleftharpoons } UDP + psychosine

Thus, the two substrates of this enzyme are UDP-galactose and sphingosine, whereas its two products are UDP and psychosine.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:sphingosine 1-beta-galactosyltransferase. Other names in common use include psychosine-UDP galactosyltransferase, galactosyl-sphingosine transferase, psychosine-uridine diphosphate galactosyltransferase, UDP-galactose:sphingosine O-galactosyl transferase, uridine diphosphogalactose-sphingosine beta-galactosyltransferase, and UDP-galactose:sphingosine 1-beta-galactotransferase. This enzyme participates in sphingolipid metabolism.

References

  1. Cleland WW, Kennedy EP (January 1960). "The enzymatic synthesis of psychosine". The Journal of Biological Chemistry. 235: 45–51. PMID 13810623.
Transferases: glycosyltransferases (EC 2.4)
2.4.1: Hexosyl-
transferases
Glucosyl-
Galactosyl-
Glucuronosyl-
Fucosyl-
Mannosyl-
2.4.2: Pentosyl-
transferases
Ribose
ADP-ribosyltransferase
Phosphoribosyltransferase
Other
Other
2.4.99: Sialyl
transferases
Enzymes
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Regulation
Classification
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