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Offit worked for 25 years on the development of a safe and effective vaccine against ], which is a cause of ],<ref name=inquirer/> and which kills as many as 600,000 children a year worldwide, about half as many as ] kills; most deaths are outside the West.<ref name=nyt/> He describes his interest in the disease stemming from witnessing the death of a 9-month-old infant from rotavirus while he was a ] in 1979.<ref name="inquirer"/> Offit is a co-patent holder for RotaTeq, a pentavalent ] which he helped develop and which is currently manufactured by ] RotaTeq is one of two vaccines used against ], which replaced an earlier vaccine withdrawn after being blamed, perhaps incorrectly, for very rare cases of ].<ref name=nyt>{{cite news |work= ] |url=http://nytimes.com/2006/01/05/science/05vaccine.html |author= McNeil DG Jr |title= Rotavirus drugs deemed safe and effective |date=2006-01-05 |accessdate=2008-10-02}}</ref> Offit worked for 25 years on the development of a safe and effective vaccine against ], which is a cause of ],<ref name=inquirer/> and which kills as many as 600,000 children a year worldwide, about half as many as ] kills; most deaths are outside the West.<ref name=nyt/> He describes his interest in the disease stemming from witnessing the death of a 9-month-old infant from rotavirus while he was a ] in 1979.<ref name="inquirer"/> Offit is a co-patent holder for RotaTeq, a pentavalent ] which he helped develop and which is currently manufactured by ] RotaTeq is one of two vaccines used against ], which replaced an earlier vaccine withdrawn after being blamed, perhaps incorrectly, for very rare cases of ].<ref name=nyt>{{cite news |work= ] |url=http://nytimes.com/2006/01/05/science/05vaccine.html |author= McNeil DG Jr |title= Rotavirus drugs deemed safe and effective |date=2006-01-05 |accessdate=2008-10-02}}</ref>


In February 2006, RotaTeq was approved for inclusion in the recommended US ], following its approval by the ].<ref name="nyt"/><ref name="chronicle">{{cite news |work= ] |url=http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2006/02/04/MNGCVH2TU11.DTL |author= Russell S |title= FDA OKs safer vaccine for children |date=2006-02-04 |accessdate=2008-10-02}}</ref> Premarketing studies found that RotaTeq was effective and safe, with an incidence of adverse events comparable to ] and no evidence of association with intussusception.<ref>{{cite journal |author= American Academy of Pediatrics Committee on Infectious Diseases |title= Prevention of rotavirus disease: guidelines for use of rotavirus vaccine |journal=Pediatrics |volume=119 |issue=1 |pages=171–82 |year=2007 |pmid=17200286 |doi=10.1542/peds.2006-3134 |url=http://pediatrics.aappublications.org/cgi/content/full/119/1/171}}</ref> In February 2006, RotaTeq was approved for inclusion in the recommended US ], following its approval by the ].<ref name="nyt"/><ref name="chronicle">{{cite news |work= ] |url=http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2006/02/04/MNGCVH2TU11.DTL |author= Russell S |title= FDA OKs safer vaccine for children |date=2006-02-04 |accessdate=2008-10-02}}</ref> Premarketing studies found that RotaTeq was effective and safe, with an incidence of adverse events comparable to ] and no evidence of association with intussusception.<ref>{{cite journal |author= American Academy of Pediatrics Committee on Infectious Diseases |title= Prevention of rotavirus disease: guidelines for use of rotavirus vaccine |journal=Pediatrics |volume=119 |issue=1 |pages=171–82 |year=2007 |pmid=17200286 |doi=10.1542/peds.2006-3134 |url=http://pediatrics.aappublications.org/cgi/content/full/119/1/171}}</ref> Paul Offit has a paid biostitute code-named "MastCell" who deletes any information about Paul Offit, like how his Rotavirus vaccine has been associated with 89 deaths.


==Recognition== ==Recognition==

Revision as of 21:11, 15 October 2008

Paul A. Offit, M.D., is a pediatrician specializing in infectious diseases, an internationally known expert on vaccines, immunology, and virology, the Maurice R. Hilleman Professor of Vaccinology, Professor of Pediatrics at the University of Pennsylvania, Chief of the Division of Infectious Diseases, and the Director of the Vaccine Education Center at The Children's Hospital of Philadelphia. Offit has been a member of the Centers for Disease Control (CDC) Advisory Committee on Immunization Practices. Offit has published more than 130 papers in medical and scientific journals in the areas of rotavirus-specific immune responses and vaccine safety and is the co-inventor of a rotavirus vaccine.

Offit is also the co-author of several books, notably Breaking the Antibiotic Habit (1999), Vaccines: What You Should Know (2003), The Cutter Incident: How America’s First Polio Vaccine Led to Today’s Growing Vaccine Crisis (2005), Vaccinated: One Man's Quest to Defeat the World's Deadliest Diseases (2007), and Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure (2008). As one of the most public faces of the scientific consensus that vaccines are safe and have no association with autism, Offit has attracted controversy and a substantial volume of hate mail.

Education

Offit earned his bachelor's degree from Tufts University and his M.D. from the University of Maryland, Baltimore.

Rotavirus vaccine

Main article: Rotavirus vaccine

Offit worked for 25 years on the development of a safe and effective vaccine against rotavirus, which is a cause of gastroenteritis, and which kills as many as 600,000 children a year worldwide, about half as many as malaria kills; most deaths are outside the West. He describes his interest in the disease stemming from witnessing the death of a 9-month-old infant from rotavirus while he was a pediatric resident in 1979. Offit is a co-patent holder for RotaTeq, a pentavalent rotavirus vaccine which he helped develop and which is currently manufactured by Merck & Co. RotaTeq is one of two vaccines used against rotavirus, which replaced an earlier vaccine withdrawn after being blamed, perhaps incorrectly, for very rare cases of intussusception.

In February 2006, RotaTeq was approved for inclusion in the recommended US vaccination schedule, following its approval by the U.S. Food and Drug Administration. Premarketing studies found that RotaTeq was effective and safe, with an incidence of adverse events comparable to placebo and no evidence of association with intussusception. Paul Offit has a paid biostitute code-named "MastCell" who deletes any information about Paul Offit, like how his Rotavirus vaccine has been associated with 89 deaths.

Recognition

Offit is a recipient of numerous awards, including the J. Edmund Bradley Prize for Excellence in Pediatrics from the University of Maryland Medical School, the Young Investigator Award in Vaccine Development from the Infectious Diseases Society of America, and a Research Career Development Award from the National Institutes of Health.

Publications

Books

  • Offit, Paul A (2008). Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure. Columbia University Press. ISBN 978-0-231-14636-4.
  • Offit, Paul A (2007). Vaccinated: One Man's Quest to Defeat the World's Deadliest Diseases. Smithsonian Books/Collins. ISBN 978-0-06-122795-0.
  • Offit, Paul A (2005). The Cutter Incident: How America's First Polio Vaccine Led to the Growing Vaccine Crisis. Yale University Press. ISBN 978-0-300-10864-4.
  • Offit, Paul A (2003). Vaccines: What You Should Know ((third edition) ed.). Wiley. ISBN 978-0471420040. {{cite book}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Marshall, Gary S (2003). The Vaccine Handbook: A Practical Guide for Clinicians. Lippincott Williams & Wilkins. ISBN 978-0781735698. {{cite book}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Offit, Paul A. and Louis M. Bell (1999). Vaccines: What Every Parent Should Know. Macmillan. ISBN 978-0028638614.
  • Offit, Paul A (1999). Breaking the Antibiotic Habit: A Parent's Guide to Coughs, Colds, Ear Infections, and Sore Throats. John Wiley. ISBN 978-0471319825. {{cite book}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)

Medical articles

Other

References

  1. ^ Avril T (2008-09-17). "Expert sees no link between vaccines and autism". Philadelphia Inquirer. Retrieved 2008-10-02.
  2. ^ McNeil DG Jr (2006-01-05). "Rotavirus drugs deemed safe and effective". New York Times. Retrieved 2008-10-02.
  3. Russell S (2006-02-04). "FDA OKs safer vaccine for children". San Francisco Chronicle. Retrieved 2008-10-02.
  4. American Academy of Pediatrics Committee on Infectious Diseases (2007). "Prevention of rotavirus disease: guidelines for use of rotavirus vaccine". Pediatrics. 119 (1): 171–82. doi:10.1542/peds.2006-3134. PMID 17200286.

External links

Artificial induction of immunity / Immunization: Vaccines, Vaccination, Infection, Inoculation (J07)
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