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Flomoxef

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Revision as of 17:14, 12 February 2011 by Rjwilmsi (talk | contribs) (clean up (DOI links) using AWB (7584))(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Flomoxef
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • (6R,7R)-7-amino]-3- sulfanylmethyl]- 7-methoxy-8-oxo-5-oxa-1-azabicyclooct-2-ene-2-carboxylic acid
CAS Number
PubChem CID
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H18F2N6O7S2
Molar mass496.46 g/mol g·mol

Flomoxef (INN) is an oxacephem antibiotic.

It has been identified as second-generation and fourth generation.

References

  1. Masuda Z, Kurosaki Y, Ishino K, Yamauchi K, Sano S (2008). "Pharmacokinetic analysis of flomoxef in children undergoing cardiopulmonary bypass and modified ultrafiltration". Gen Thorac Cardiovasc Surg. 56 (4): 163–9. doi:10.1007/s11748-007-0208-5. PMID 18401677. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. Ito M, Ishigami T (1991). "The meaning of the development of flomoxef and clinical experience in Japan". Infection. 19 Suppl 5: S253–7. PMID 1783441.
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Antibacterials active on the cell wall and envelope (J01C-J01D)
β-lactams
(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases
)
Penicillins (Penams)
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spectrum
β-lactamase sensitive
(1st generation)
β-lactamase resistant
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Extended
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Aminopenicillins (3rd generation)
Carboxypenicillins (4th generation)
Ureidopenicillins (4th generation)
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Cephalosporins
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1st generation
2nd generation
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Veterinary
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β-lactamase inhibitors
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  • Inhibits PG elongation and crosslinking: Ramoplanin
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