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Desoxycorticosterone pivalate

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(Redirected from Desoxycortone pivalate) Chemical compound Pharmaceutical compound
Desoxycorticosterone pivalate
Clinical data
Trade namesZycortal, Percorten V, Percorten M, Neocortin Depositum, Neocortodina Depositum, Neodin Depositum
Other namesDOCP; Deoxycorticosterone pivalate; Desoxycortone pivalate; Deoxycortone pivalate; Percoten pivalate; Desoxycorticosterone trimethylacetate; Desoxycorticosterone trimethyl acetate; DCT; DOC-TMA; SC-46312; 21-Hydroxypregn-4-ene-3,20-dione pivalate; 21-(2,2-Dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione
Routes of
administration
Intramuscular injection
Drug classCorticosteroid; Mineralocorticoid
ATC code
Identifiers
IUPAC name
  • phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.011.242 Edit this at Wikidata
Chemical and physical data
FormulaC26H38O4
Molar mass414.586 g·mol
3D model (JSmol)
SMILES
  • C12CC3(1CC2C(=O)COC(=O)C(C)(C)C)CCC4=CC(=O)CC34C
InChI
  • InChI=1S/C26H38O4/c1-24(2,3)23(29)30-15-22(28)21-9-8-19-18-7-6-16-14-17(27)10-12-25(16,4)20(18)11-13-26(19,21)5/h14,18-21H,6-13,15H2,1-5H3/t18-,19-,20-,21+,25-,26-/m0/s1
  • Key:VVOIQBFMTVCINR-WWMZEODYSA-N

Deoxycorticosterone pivalate (DOCP), also known as desoxycorticosterone trimethyl acetate (DOC-TMA or DCT) and sold under the brand names Zycortal, Percorten V, and Percorten M, is a mineralocorticoid medication and a mineralocorticoid ester. It is formulated as a microcrystalline aqueous suspension, is administered by intramuscular injection at regular intervals, and has a prolonged duration of action. The medication is the C21 pivalate (trimethylacetate) ester of 11-deoxycorticosterone.

See also

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 665–. ISBN 978-1-4757-2085-3.
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 307–. ISBN 978-3-88763-075-1.
  3. Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 93–. ISBN 978-94-011-4439-1.
  4. Negwer M, Scharnow HG (4 October 2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 2721. ISBN 978-3-527-30247-5. Deoxycortone trimethylacetate, Desoxycorticosterone pivalate. Neocortin depositum, Neocortodina depositum. Neodin-Depositum, Percorten M, Percorten pivalate U Mineralocorticoid (salt-regulating)
  5. Hager HH, Kern W, List PH, Roth HJ (29 July 2013). Hagers Handbuch der Pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Ärzte und Medizinalbeamte: Wirkstoffgruppen II Chemikalien und Drogen (A-AL). Springer-Verlag. pp. 108–109. ISBN 978-3-662-25655-8.


Mineralocorticoids and antimineralocorticoids (H02)
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