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Cortisone acetate

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Chemical compound Pharmaceutical compound
Cortisone acetate
Clinical data
Trade namesAdreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others
Other namesCortisone 21-acetate; 17α,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate
Drug classCorticosteroid; Glucocorticoid
Identifiers
IUPAC name
  • phenanthren-17-yl]-2-oxoethyl] acetate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.006 Edit this at Wikidata
Chemical and physical data
FormulaC23H30O6
Molar mass402.487 g·mol
3D model (JSmol)
SMILES
  • CC(=O)OCC(=O)1(CC21(CC(=O)32CCC4=CC(=O)CC34C)C)O
InChI
  • InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1
  • Key:ITRJWOMZKQRYTA-RFZYENFJSA-N

Cortisone acetate (brand names Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others) is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed (under prescription) in many countries throughout the world, including in the United States, the United Kingdom, and various other European countries. It is the C21 acetate ester of cortisone, and acts as a prodrug of cortisone in the body.

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 317–. ISBN 978-1-4757-2085-3.
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 276–. ISBN 978-3-88763-075-1.
  3. Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 85–. ISBN 978-94-011-4439-1.
  4. Løvås K, Husebye ES (December 2003). "Replacement therapy in Addison's disease". Expert Opinion on Pharmacotherapy. 4 (12): 2145–2149. doi:10.1517/14656566.4.12.2145. PMID 14640913. S2CID 37628998.
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