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OR10R2
Identifiers
Aliases	OR10R2, OR1-8, OR10R2Q, olfactory receptor family 10 subfamily R member 2
External IDs	HomoloGene: 121586; GeneCards: OR10R2; OMA:OR10R2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q23.1 Start 158,472,220 bp End 158,480,936 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in organ system thyroid gland blood multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 343406 n/a Ensembl ENSG00000198965 n/a UniProt Q8NGX6 n/a RefSeq (mRNA) NM_001004472 NM_001395749 n/a RefSeq (protein) NP_001004472 n/a Location (UCSC) Chr 1: 158.47 – 158.48 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Olfactory receptor 10R2 is a protein that in humans is encoded by the OR10R2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000198965 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. ^ "Entrez Gene: OR10R2 olfactory receptor, family 10, subfamily R, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

• OR10R2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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