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OR2Y1
Identifiers
Aliases	OR2Y1, OR5-2, olfactory receptor family 2 subfamily Y member 1
External IDs	MGI: 3031220; HomoloGene: 86692; GeneCards: OR2Y1; OMA:OR2Y1 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) Band 5q35.3 Start 180,739,123 bp End 180,740,058 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B1.2 Start 49,355,873 bp End 49,362,542 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in salivary gland multicellular organism n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 134083 257888 Ensembl ENSG00000174339 ENSMUSG00000108167 UniProt Q8NGV0 Q7TQT0 RefSeq (mRNA) NM_001001657 NM_001011741 RefSeq (protein) NP_001001657 NP_001011741 Location (UCSC) Chr 5: 180.74 – 180.74 Mb Chr 11: 49.36 – 49.36 Mb PubMed search
Wikidata
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Olfactory receptor 2Y1 is a protein that in humans is encoded by the OR2Y1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000174339 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000108167 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: OR2Y1 olfactory receptor, family 2, subfamily Y, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2Y1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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• Olfactory receptors