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OR6K6
Identifiers
Aliases	OR6K6, OR1-21, olfactory receptor family 6 subfamily K member 6
External IDs	MGI: 3030065; HomoloGene: 17363; GeneCards: OR6K6; OMA:OR6K6 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q23.1 Start 158,754,720 bp End 158,755,891 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 H3 Start 173,940,777 bp End 173,948,728 bp
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 128371 404222 Ensembl ENSG00000180433 ENSMUSG00000046486 UniProt Q8NGW6 E9Q0M4 RefSeq (mRNA) NM_001005184 NM_001005520 RefSeq (protein) NP_001005184 NP_001005520 Location (UCSC) Chr 1: 158.75 – 158.76 Mb Chr 1: 173.94 – 173.95 Mb PubMed search
Wikidata
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Olfactory receptor 6K6 is a protein that in humans is encoded by the OR6K6 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000180433 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000046486 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: OR6K6 olfactory receptor, family 6, subfamily K, member 6".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

• OR6K6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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